heroin dependence

Summary
Definition
An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.
Super Class
opiate dependence
Disease Ontology
DOID:9976
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
Related Genes
Displaying entries 1 - 10 of 26 in total
Gene ID Gene Symbol Description Source
43 ACHE acetylcholinesterase (Yt blood group)
148 ADRA1A adrenoceptor alpha 1A
217 ALDH2 aldehyde dehydrogenase 2 family member
1129 CHRM2 cholinergic receptor muscarinic 2
1312 COMT catechol-O-methyltransferase
1385 CREB1 cAMP responsive element binding protein 1
1555 CYP2B6 cytochrome P450 family 2 subfamily B member 6
1557 CYP2C19 cytochrome P450 family 2 subfamily C member 19
1813 DRD2 dopamine receptor D2
1815 DRD4 dopamine receptor D4
Displaying all 5 entries
Gene ID Gene Symbol Description Source
24185 Akt1 AKT serine/threonine kinase 1
24415 Grm2 glutamate metabotropic receptor 2
29237 Penk proenkephalin
29335 Oprk1 opioid receptor, kappa 1
81646 Creb1 cAMP responsive element binding protein 1

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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