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Guidelines

MIRAGE

popeye domain cAMP effector 1

Summary

Gene Symbol

popdc1

Organism

Xenopus tropicalis (tropical clawed frog)

External Links

NCBI Gene

100144641

PubChem

100144641

Alliance of Genome Resources

Xenbase:XB-GENE-484277

Annotation

Keyword

Cell adhesion
Cell membrane
Developmental protein
Glycoprotein
Reference proteome
Tight junction
Transmembrane helix
cAMP-binding

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8J0SKL8
B1H1G2	Popeye domain-containing protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
positive regulation of receptor recycling	ISS
response to ischemia	ISS
cell adhesion	IEA
heart development	ISS
skeletal muscle tissue development	ISS

GO Hierarchy

biological process

cellular process [inference]

cell-substrate adhesion [inference]

substrate adhesion-dependent cell spreading

cell-cell adhesion [inference]

epithelial cell-cell adhesion

vesicle-mediated transport

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

muscle tissue development [inference]

skeletal muscle tissue development

animal organ development [inference]

heart development

response to stimulus [inference]

response to stress [inference]

response to ischemia

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

regulation of macromolecule metabolic process [inference]

regulation of receptor recycling [inference]

positive regulation of receptor recycling

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

regulation of signaling [inference]

regulation of receptor recycling [inference]

positive regulation of receptor recycling

positive regulation of signaling [inference]

positive regulation of receptor recycling

regulation of locomotion [inference]

positive regulation of locomotion

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

positive regulation of signaling [inference]

positive regulation of receptor recycling

positive regulation of locomotion

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of biological quality [inference]

regulation of cell shape

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of hydrolase activity [inference]

regulation of GTPase activity

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	IEA
caveola	ISS
caveola	IEA
bicellular tight junction	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

sarcolemma

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

lateral plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

bicellular tight junction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
structural molecule activity	ISS
cAMP binding	IEA

GO Hierarchy

molecular function

structural molecule activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

cyclic nucleotide binding [inference]

cAMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

ion binding [inference]

anion binding [inference]

cAMP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

cyclic nucleotide binding [inference]

cAMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Blood vessel epicardial substance

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
cAMP binding
regulation of membrane potential
striated muscle cell differentiation

Displaying **all 2** entries
InterPro
Cyclic nucleotide-binding domain superfamily
Popeye protein

Ortholog

Displaying entries **1 - 10** of 11 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus laevis	11149	Xenbase:XB-GENE-6254222
Danio rerio	23828	ZFIN:ZDB-GENE-040624-11
Drosophila melanogaster	64082	FB:FBgn0031150
Drosophila melanogaster	64091	FB:FBgn0031150
Drosophila melanogaster	64208	FB:FBgn0031150
Drosophila melanogaster	78977	FB:FBgn0031150
Danio rerio	365603	ZFIN:ZDB-GENE-040624-11
Xenopus laevis	394408	Xenbase:XB-GENE-6254222
Danio rerio	415107	ZFIN:ZDB-GENE-040624-11
Xenopus laevis	779321	Xenbase:XB-GENE-865066

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025