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popeye domain cAMP effector 1

Summary

Gene Symbol

Popdc1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

23828

PubChem

23828

Alliance of Genome Resources

MGI:1346013

Annotation

Keyword

Cell adhesion
Cell membrane
Developmental protein
Glycoprotein
Phosphoprotein
Reference proteome
Tight junction
Transmembrane helix
cAMP-binding

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9ES83	Popeye domain-containing protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
positive regulation of receptor recycling	IDA	20057356
regulation of heart rate	IMP	22354168
hematopoietic progenitor cell differentiation	IGI	24029230
response to ischemia	IMP	24066022
heart development	ISS

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

substrate adhesion-dependent cell spreading

cell-cell adhesion [inference]

epithelial cell-cell adhesion

vesicle-mediated transport

membrane docking [inference]

organelle localization by membrane tethering [inference]

vesicle docking

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development [inference]

cardiac pacemaker cell development [inference]

sinoatrial node cell development

cardiac cell development [inference]

cardiac muscle cell development [inference]

cardiac pacemaker cell development [inference]

sinoatrial node cell development

cell motility [inference]

cell migration [inference]

cell migration involved in heart development

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

muscle tissue development [inference]

skeletal muscle tissue development

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development [inference]

cardiac pacemaker cell development [inference]

sinoatrial node cell development

cardiac cell development [inference]

cardiac muscle cell development [inference]

cardiac pacemaker cell development [inference]

sinoatrial node cell development

animal organ development [inference]

heart development

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development [inference]

cardiac pacemaker cell development [inference]

sinoatrial node cell development

cardiac cell development [inference]

cardiac muscle cell development [inference]

cardiac pacemaker cell development [inference]

sinoatrial node cell development

response to stimulus [inference]

response to stress [inference]

response to ischemia

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

organelle localization [inference]

organelle localization by membrane tethering [inference]

vesicle docking

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

regulation of macromolecule metabolic process [inference]

regulation of receptor recycling [inference]

positive regulation of receptor recycling

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

regulation of signaling [inference]

regulation of receptor recycling [inference]

positive regulation of receptor recycling

positive regulation of signaling [inference]

positive regulation of receptor recycling

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

regulation of endocytic recycling

regulation of vesicle-mediated transport [inference]

regulation of endocytic recycling

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of endocytic recycling

regulation of locomotion [inference]

positive regulation of locomotion

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

positive regulation of signaling [inference]

positive regulation of receptor recycling

positive regulation of locomotion

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of cellular process [inference]

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of endocytic recycling

regulation of vesicle-mediated transport [inference]

regulation of endocytic recycling

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of heart rate

regulation of biological quality [inference]

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of hydrolase activity [inference]

regulation of GTPase activity

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	IDA	18541910 20057356 22354168
caveola	IDA	24066022
bicellular tight junction	ISO
bicellular tight junction	IDA	16188940

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

sarcolemma

plasma membrane region [inference]

cell projection membrane

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

lateral plasma membrane

cell junction

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

bicellular tight junction

Displaying **all 5** entries
GO Term	Evidence Code	PMID
structural molecule activity	ISS
structural molecule activity	ISO
protein binding	IPI	16188940 18541910 20057356 22354168 24048452 24066022
cAMP binding	IDA	22354168
cAMP binding	IBA

GO Hierarchy

molecular function

structural molecule activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

cyclic nucleotide binding [inference]

cAMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

ion binding [inference]

anion binding [inference]

cAMP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

cyclic nucleotide binding [inference]

cAMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Blood vessel epicardial substance

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
cAMP binding
regulation of membrane potential
striated muscle cell differentiation

Displaying **all 2** entries
InterPro
Cyclic nucleotide-binding domain superfamily
Popeye protein

Ortholog

Displaying entries **1 - 10** of 87 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	11149	Xenbase:XB-GENE-484277	HUMAN85888
Xenopus tropicalis	23828	Xenbase:XB-GENE-484277
Drosophila melanogaster	64082	FB:FBgn0031150
Drosophila melanogaster	64091	FB:FBgn0031150
Drosophila melanogaster	64208	FB:FBgn0031150
Drosophila melanogaster	78977	FB:FBgn0031150
Rattus norvegicus	365603	Xenbase:XB-GENE-484277	RATNO21560
Xenopus tropicalis	394408	Xenbase:XB-GENE-484277
Danio rerio	415107	Xenbase:XB-GENE-484277	DANRE10223
Pan troglodytes	472204		PANTR38773