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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
proprotein convertase subtilisin/kexin type 2
Summary
- Gene Symbol
-
- PCSK2
- Organism
- Pongo abelii (Sumatran orangutan)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Coiled coil
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A2J8VD76 |
|
| Q5REC2 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| insulin processing |
|
|
| protein autoprocessing |
|
|
| peptide hormone processing | ||
| nervous system development |
|
|
| enkephalin processing |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| secretory granule |
|
|
| neuron projection | ||
| nucleoplasm |
|
|
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- FURIN
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| peptide hormone processing |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 103214696 | CHLSB07873 | |||
| 103256179 | CARSF29075 | |||
| 103680513 | URSMA25107 | |||
| 103747731 | NANGA20946 | |||
| 103822198 | SERCA16524 | |||
| 104676602 | RHIRO14864 | |||
| 105486861 | MACNE32815 | |||
| 105539280 | MANLE10947 | |||
| 105582050 | CERAT03062 | |||
| 105732617 | AOTNA21104 |
