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MIRAGE
proprotein convertase subtilisin/kexin type 2
Summary
- Gene Symbol
-
- PCSK2
- Organism
- Pongo abelii (Sumatran orangutan)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Coiled coil
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A2J8VD76 |
|
| Q5REC2 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| nervous system development |
|
|
| peptide hormone processing | ||
| protein autoprocessing |
|
|
| insulin processing |
|
|
| enkephalin processing |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| nucleoplasm |
|
|
| membrane | ||
| transport vesicle |
|
|
| secretory granule |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Proprotein convertase subtilisin/kexin type
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| peptide hormone processing |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5126 | HUMAN56158 | ||
| 18549 | MOUSE35600 | ||
| 25121 | RATNO26436 | ||
| 281968 | BOVIN04526 | ||
| 445533 | PIGXX11301 | ||
| 458106 | PANTR24399 | ||
| 485757 | CANLF09277 | ||
| 695730 | MACMU02549 | ||
| 100004460 | DANRE06459 | ||
| 100033262 | MONDO08876 |
