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macrophage expressed 1

Summary

Gene Symbol

MPEG1

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100172369
PubChem: 100172369

Annotation

Keyword

Adaptive immunity
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Innate immunity
Reference proteome
Signal
Transmembrane beta strand
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5RBP9	Perforin-2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
antigen processing and presentation of exogenous peptide antigen
defense response to Gram-negative bacterium
adaptive immune response
defense response to Gram-positive bacterium
antigen processing and presentation of exogenous peptide antigen via MHC class I

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

adaptive immune response

innate immune response [inference]

antibacterial innate immune response

antigen processing and presentation [inference]

dendritic cell antigen processing and presentation

antigen processing and presentation of exogenous antigen [inference]

antigen processing and presentation of exogenous peptide antigen

antigen processing and presentation of exogenous peptide antigen via MHC class I

antigen processing and presentation of peptide antigen [inference]

antigen processing and presentation of peptide antigen via MHC class I [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I

antigen processing and presentation of exogenous peptide antigen

antigen processing and presentation of exogenous peptide antigen via MHC class I

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

antibacterial innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

antibacterial innate immune response

immune response [inference]

adaptive immune response

innate immune response [inference]

antibacterial innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

antibacterial innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

antibacterial innate immune response

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasmic vesicle
phagolysosome membrane
phagocytic vesicle
phagocytic vesicle membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

phagolysosome membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

phagolysosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

phagolysosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endocytic vesicle [inference]

phagocytic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endocytic vesicle [inference]

phagocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endocytic vesicle [inference]

phagocytic vesicle

Displaying 1 entry
GO Term	Evidence Code	PMID
wide pore channel activity

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

passive transmembrane transporter activity [inference]

channel activity [inference]

wide pore channel activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

macrophage expressed 1

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
adaptive immune response

Displaying **all 2** entries
InterPro
Macrophage-expressed gene 1 protein
Membrane attack complex component/perforin (MACPF) domain

Ortholog

Displaying entries **11 - 20** of 86 in total

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Species	Gene ID	Orthologous MAtrix
Ornithorhynchus anatinus	100074777	ORNAN17180
Taeniopygia guttata	100230543	TAEGU25995
Oryctolagus cuniculus	100353655	RABIT01416
Callithrix jacchus	100397678	CALJA03426
Ailuropoda melanoleuca	100476674	AILME03508
Meleagris gallopavo	100538524	MELGA10699
Anolis carolinensis	100565090	ANOCA00696
Nomascus leucogenys	100595896	NOMLE28162
Loxodonta africana	100674578	LOXAF01225
Oreochromis niloticus	100697252	ORENI10142