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CXADR Ig-like cell adhesion molecule

Summary

Gene Symbol

CXADR

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100174624
PubChem: 100174624

Annotation

Keyword

Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Palmitate
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Tight junction
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5R764

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
mitochondrion organization
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
heart development
germ cell migration
epithelial structure maintenance

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

cell communication [inference]

cell communication involved in cardiac conduction [inference]

AV node cell to bundle of His cell communication

cell adhesion [inference]

cell-cell adhesion [inference]

homotypic cell-cell adhesion

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

cellular process involved in reproduction in multicellular organism [inference]

germ cell migration

actin filament-based process [inference]

actin cytoskeleton organization

cellular developmental process [inference]

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

cell motility [inference]

cell migration [inference]

germ cell migration

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

cytoskeleton organization [inference]

actin cytoskeleton organization

cell junction organization [inference]

cell-cell junction organization

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

germ cell migration

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

animal organ development [inference]

heart development

cellular developmental process [inference]

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
acrosomal vesicle
nucleus
cytoplasm
plasma membrane
adherens junction

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

membrane microdomain [inference]

membrane raft

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

cell-cell contact zone [inference]

intercalated disc

tight junction [inference]

bicellular tight junction

site of polarized growth [inference]

growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

actin-based cell projection [inference]

filopodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

cell body

Displaying **all 4** entries
GO Term	Evidence Code	PMID
beta-catenin binding
PDZ domain binding
cell adhesion molecule binding	IEA	30032202
connexin binding

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

protein domain specific binding [inference]

PDZ domain binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Coxsackievirus and adenovirus receptor

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cell adhesion molecule binding
homotypic cell-cell adhesion

Displaying **all 6** entries
InterPro
Immunoglobulin V-set domain
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **1 - 10** of 74 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	1525	HUMAN58104
Mus musculus	13052	MOUSE18651
Rattus norvegicus	89843	RATNO04836
Bos taurus	281733	BOVIN14297
Sus scrofa	397333	PIGXX05957
Canis lupus familiaris	403772	CANLF12765
Pan troglodytes	473920	PANTR25430
Macaca mulatta	716409	MACMU32800
Danio rerio	791793	DANRE01180
Equus caballus	100067795	HORSE24978

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OrthoDB (Group)

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Acknowledgements