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alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A

Summary

Gene Symbol

MGAT4A

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100190826
KEGG Gene ID: pon:100190826
PubChem: 100190826

Annotation

Keyword

Coiled coil
Glycoprotein
Glycosyltransferase
Golgi apparatus
Metal-binding
Phosphoprotein
Reference proteome
Secreted
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5REP8	N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation	IEA	30032202
N-glycan processing
glyoxylate metabolic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
Golgi membrane
extracellular region
peroxisome
endoplasmic reticulum	IEA	30032202
endoplasmic reticulum-Golgi intermediate compartment	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

Golgi stack

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
acetylglucosaminyltransferase activity	IEA	30032202
alanine-glyoxylate transaminase activity
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
protein homodimerization activity
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

transferase activity, transferring nitrogenous groups [inference]

transaminase activity [inference]

alanine-glyoxylate transaminase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alpha-1,3-mannosyl-glycoprotein 4-beta-n-acetylglucosaminyltransferase a

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
acetylglucosaminyltransferase activity
protein N-linked glycosylation

Displaying 1 entry
InterPro
Glycosyl transferase family 54

KEGG BRITE Database

Orthology

K00738

Name

alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145]

References

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05987	2.4.1.145	G39213VZ	G29011JC

Rhea

RHEA:16057

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.145

PMID

Ortholog

Displaying entries **1 - 10** of 88 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	11320	HUMAN63973
Mus musculus	269181	MOUSE29818
Bos taurus	282276	BOVIN02011
Rattus norvegicus	367252	RATNO44023
Pan troglodytes	459434	PANTR28294
Canis lupus familiaris	474562	CANLF01772
Macaca mulatta	708094	MACMU08505
Monodelphis domestica	100013784	MONDO32609
Ornithorhynchus anatinus	100093525	ORNAN06747
Taeniopygia guttata	100218916	TAEGU11504

GlyTouCan

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UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements