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reversion-inducing-cysteine-rich protein with kazal motifs

Summary

Gene Symbol

reck

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

100334698

PubChem

100334698

Alliance of Genome Resources

ZFIN:ZDB-GENE-070117-37

Annotation

Keyword

Cell membrane
Disulfide bond
GPI-anchor
Reference proteome
Repeat
Serine protease inhibitor
Signal
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A0R4IKU3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
vasculature development	IMP	26051822
blood vessel maturation	IBA
sprouting angiogenesis	IMP	26051822
sprouting angiogenesis	IBA
Wnt signaling pathway	IMP	26051822

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

blood vessel maturation

anatomical structure formation involved in morphogenesis [inference]

angiogenesis [inference]

sprouting angiogenesis

anatomical structure development [inference]

tissue development [inference]

ganglion development [inference]

dorsal root ganglion development

system development [inference]

vasculature development

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metallopeptidase activity [inference]

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metallopeptidase activity [inference]

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metallopeptidase activity [inference]

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway

positive regulation of canonical Wnt signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration [inference]

regulation of cell migration involved in sprouting angiogenesis

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway

positive regulation of canonical Wnt signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of establishment of blood-brain barrier

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway

positive regulation of canonical Wnt signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of establishment of blood-brain barrier

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of cell cycle

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration [inference]

regulation of cell migration involved in sprouting angiogenesis

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration [inference]

regulation of cell migration involved in sprouting angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

regulation of metallopeptidase activity [inference]

regulation of metalloendopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

negative regulation of metallopeptidase activity [inference]

negative regulation of metalloendopeptidase activity

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	IDA	27979830
plasma membrane	IBA
side of membrane
Wnt signalosome	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

Wnt signalosome

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

side of membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
endopeptidase inhibitor activity	IBA
serine-type endopeptidase inhibitor activity
metalloendopeptidase inhibitor activity	ISS
metalloendopeptidase inhibitor activity	IEA
coreceptor activity	ISS