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ST3 beta-galactoside alpha-2,3-sialyltransferase 2

Summary

Gene Symbol

ST3GAL2

Organism

Otolemur garnettii (small-eared galago)

External Links

NCBI Gene: 100943456
KEGG Gene ID: oga:100943456
PubChem: 100943456

Annotation

Keyword

Glycoprotein
Golgi apparatus
Reference proteome
Secreted
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
H0X5I5	Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase Monosialoganglioside sialyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
protein glycosylation	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

Displaying 1 entry
GO Term	Evidence Code	PMID
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity [inference]

beta-galactoside (CMP) alpha-2,3-sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Sialyltransferase

Functional Category

H: Coenzyme transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
sialyltransferase activity
transferase activity

Displaying **all 2** entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29

KEGG BRITE Database

Orthology

K03368

Name

beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.3.2 2.4.3.4]

References

8144500

Reactions

Displaying **all 5** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05949	2.4.3.2	G37184KW	G40183QN
R05942	2.4.3.2	G48558GR	G46677TE
R05957	2.4.3.2	G21856LC	G03277YI
R05967	2.4.3.2	G99053DY	G32254QI
R05913	2.4.3.4	G00031MO	G65562ZE

Rhea

RHEA:52380

a β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl derivative + H⁺ + CMP

Enzyme

2.4.3.2

PMID

RHEA:18021

CMP-N-acetyl-β-neuraminate + a ganglioside GM1 (d18:1(4E))

H⁺ + CMP + a ganglioside GD1a (d18:1(4E))

Enzyme

2.4.3.2

PMID

RHEA:21616

a β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + H⁺ + CMP

Enzyme

2.4.3.4

PMID

Ortholog

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	6483	9606_0:001cfc	HUMAN29481
Mus musculus	20444		MOUSE58240
Rattus norvegicus	64442		RATNO14530
Bos taurus	444879		BOVIN10115
Danio rerio	445562		DANRE14679
Ciona intestinalis	445728		CIOIN05215
Pan troglodytes	454214		PANTR12758
Canis lupus familiaris	489714		CANLF15964
Macaca mulatta	709319	9544_0:004c45	MACMU27439
Monodelphis domestica	100011298		MONDO07846

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements