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Standards Ontologies Notations
phosphatase and tensin homolog

Summary
Gene Symbol
  • PTEN
Organism
Papio anubis (olive baboon)
NCBI Gene
101016586
KEGG Gene ID
panu:101016586
PubChem
101016586
Gene Ontology (GO)
Displaying entry 6 - 6 of 6 in total
GO Term Evidence Code PMID
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO Hierarchy
Displaying all 5 entries
GO Term Evidence Code PMID
protein tyrosine/serine/threonine phosphatase activity
protein tyrosine phosphatase activity
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Cercopithecoidea
Group Name
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Functional Category
  • H: Coenzyme transport and metabolism
  • I: Lipid transport and metabolism
  • T: Signal transduction mechanisms
Displaying entries 21 - 30 of 36 in total
Gene Ontology
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
negative regulation of protein phosphorylation
negative regulation of vascular associated smooth muscle cell proliferation
negative regulation of wound healing, spreading of epidermal cells
nervous system development
phosphatidylinositol phosphate phosphatase activity
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
phosphoprotein phosphatase activity
positive regulation of ubiquitin-dependent protein catabolic process
Displaying all 10 entries
InterPro
Bifunctional phosphatidylinositol trisphosphate phosphatase/dual specificity phosphatase PTEN
C2 domain superfamily
PTEN, phosphatase domain
Protein-tyrosine phosphatase, active site
Protein-tyrosine phosphatase, catalytic
Protein-tyrosine phosphatase-like
Tensin phosphatase, C2 domain
Tensin-type phosphatase domain
Tyrosine-specific protein phosphatase, PTPase domain
Tyrosine-specific protein phosphatases domain
KEGG BRITE Database
Orthology
K01110
Name
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
References
Ortholog
Displaying entries 11 - 20 of 77 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
100358716 RABIT06803
100469483 AILME17675
100552870 ANOCA16519
100605147 NOMLE26489
100660561 LOXAF15638
100695712 ORENI14286
101039215 SAIBB04613
101091813 FELCA26459
101119351 SHEEP11412
101171856 ORYLA04962
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024