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Standards Ontologies Notations
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

Summary
Gene Symbol
  • ST8SIA1
Organism
Gorilla gorilla gorilla (western lowland gorilla)
NCBI Gene
101134419
KEGG Gene ID
ggo:101134419
PubChem
101134419
Annotation
Keyword
  • Disulfide bond
  • Glycoprotein
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Sphingolipid metabolism
  • Transferase
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
G3QGC6
  • Alpha-2,8-sialyltransferase 8A
  • Ganglioside GD3 synthase
  • Sialyltransferase 8A
  • Sialyltransferase St8Sia I
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 3 entries
GO Term Evidence Code PMID
protein glycosylation
oligosaccharide metabolic process
N-glycan processing
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Hominidae
Group Name
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
Functional Category
  • K: Transcription
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 8 entries
Gene Ontology
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
cell population proliferation
cellular response to heat
epithelial cell proliferation
positive regulation of epithelial cell proliferation
sialyltransferase activity
sphingolipid metabolic process
transferase activity
Displaying all 3 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
Sialyltransferase
KEGG BRITE Database
Orthology
K03371
Name
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.3.8]
References
Reactions
Displaying all 4 entries
KEGG Reaction Enzyme Acceptor Product
R13175
R06032
R05947
R05940
Rhea

RHEA:19313

an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + H+ + CMP
Enzyme
PMID
Ortholog
Displaying entries 1 - 10 of 76 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
6489 9606_1:003205 HUMAN11629
20449 MOUSE47956
25280 RATNO31134
282352 BOVIN30100
465341 9598_0:00379c PANTR06305
477672 CANLF10982
553210 DANRE33846
706707 MACMU03935
100011205 MONDO35153
100080234 ORNAN14742
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024