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ADAM metallopeptidase domain 8

Summary

Gene Symbol

ADAM8

Organism

Homo sapiens (human)

External Links

NCBI Gene

101

PubChem

101

Alliance of Genome Resources

HGNC:215

Annotation

Keyword

3D-structure
Alternative splicing
Disulfide bond
EGF-like domain
Glycoprotein
Integrin
Metal-binding
Metalloprotease
Reference proteome
Signal
Transmembrane helix
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q14C66
P78325	Cell surface antigen MS2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 33 in total

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GO Term	Evidence Code	PMID
positive regulation of protein processing	NAS	17548643
regulation of cell-cell adhesion	IDA	17548643
regulation of cell-cell adhesion	IBA
extracellular matrix disassembly	TAS
signal release	IDA	12777399

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

leukocyte migration involved in inflammatory response

leukocyte chemotaxis [inference]

lymphocyte chemotaxis

mononuclear cell migration [inference]

lymphocyte migration [inference]

lymphocyte chemotaxis

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

signal transduction [inference]

intracellular signal transduction [inference]

canonical NF-kappaB signal transduction

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte migration involved in inflammatory response

leukocyte chemotaxis [inference]

lymphocyte chemotaxis

mononuclear cell migration [inference]

lymphocyte migration [inference]

lymphocyte chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

lymphocyte chemotaxis

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

extracellular matrix disassembly

extracellular structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix disassembly

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix disassembly

export from cell [inference]

secretion by cell [inference]

signal release

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

lymphocyte chemotaxis

response to stimulus [inference]

response to stress [inference]

response to hypoxia [inference]

cellular response to hypoxia

defense response [inference]

inflammatory response

cellular response to stress [inference]

cellular response to hypoxia

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia [inference]

cellular response to hypoxia

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

signal release

export from cell [inference]

secretion by cell [inference]

signal release

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of immune response [inference]

positive regulation of innate immune response

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of mononuclear cell migration [inference]

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of lymphocyte migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of T cell migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of thymocyte migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of fibronectin-dependent thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of eosinophil migration [inference]

positive regulation of eosinophil migration

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of immune response [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response

positive regulation of immune response [inference]

positive regulation of innate immune response

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor (ligand) superfamily member 11 production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor (ligand) superfamily member 11 production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein processing [inference]

positive regulation of protein processing

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor (ligand) superfamily member 11 production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein processing [inference]

positive regulation of protein processing

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein processing [inference]

positive regulation of protein processing

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of mononuclear cell migration [inference]

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of lymphocyte migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of T cell migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of thymocyte migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of fibronectin-dependent thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of eosinophil migration [inference]

positive regulation of eosinophil migration

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of immune response [inference]

positive regulation of innate immune response

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process [inference]

positive regulation of thymocyte apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell adhesion

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of immune response [inference]

positive regulation of innate immune response

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response

regulation of innate immune response [inference]

positive regulation of innate immune response

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of immune response [inference]

positive regulation of innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response

positive regulation of immune response [inference]

positive regulation of innate immune response

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

canonical NF-kappaB signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell adhesion

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor (ligand) superfamily member 11 production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing [inference]

positive regulation of protein processing

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process [inference]

positive regulation of thymocyte apoptotic process

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of leukocyte apoptotic process [inference]

regulation of lymphocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process [inference]

positive regulation of thymocyte apoptotic process

regulation of T cell apoptotic process [inference]

positive regulation of T cell apoptotic process [inference]

positive regulation of thymocyte apoptotic process

regulation of thymocyte apoptotic process [inference]

positive regulation of thymocyte apoptotic process

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process [inference]

positive regulation of thymocyte apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process [inference]

positive regulation of thymocyte apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of protein maturation [inference]

positive regulation of protein processing

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of T cell apoptotic process [inference]

positive regulation of thymocyte apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell adhesion

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of mononuclear cell migration [inference]

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of lymphocyte migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of T cell migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of thymocyte migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of fibronectin-dependent thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of eosinophil migration [inference]

positive regulation of eosinophil migration

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation

positive regulation of neutrophil extravasation

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of T cell migration [inference]

positive regulation of thymocyte migration [inference]

positive regulation of fibronectin-dependent thymocyte migration

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of eosinophil migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor (ligand) superfamily member 11 production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tissue remodeling [inference]

regulation of bone remodeling [inference]

regulation of bone resorption [inference]

positive regulation of bone resorption

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
podosome	IDA	15220135
cytoplasm	IDA	18397961
plasma membrane	TAS
plasma membrane	IDA	17548643 18397961
cell surface	IDA	17548643

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

alpha9-beta1 integrin-ADAM8 complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

bounding membrane of organelle [inference]

secretory granule membrane [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle [inference]

phagolysosome

secretory vesicle [inference]

secretory granule [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

secondary lysosome [inference]

phagolysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle [inference]

phagolysosome

secretory vesicle [inference]

secretory granule [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

podosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

secondary lysosome [inference]

phagolysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle [inference]

phagolysosome

secretory vesicle [inference]

secretory granule [inference]

intracellular non-membrane-bounded organelle [inference]

podosome

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
metalloendopeptidase activity	IBA
serine-type endopeptidase activity	TAS
calcium ion binding	ISS
protein binding	IPI	15574124 17548643 25825872
metallopeptidase activity	IDA	12777399 15220135 17548643

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

binding [inference]

protein binding

signaling receptor binding [inference]

cytokine receptor binding [inference]

tumor necrosis factor receptor superfamily binding

immunoglobulin receptor binding

cell adhesion molecule binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Disintegrin

Functional Category

M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis

Displaying **all 9** entries
InterPro
ADAM, cysteine-rich domain
Disintegrin domain superfamily
Disintegrin domain
Disintegrin, conserved site
EGF-like domain
Metallopeptidase, catalytic domain superfamily
Peptidase M12B, ADAM/reprolysin
Peptidase M12B, propeptide
Reprolysin domain, adamalysin-type

Ortholog

Displaying entries **11 - 20** of 67 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	11492	FB:FBgn0265140
Mus musculus	11501	ZFIN:ZDB-GENE-070808-1	MOUSE57441
Drosophila melanogaster	11502	FB:FBgn0265140
Drosophila melanogaster	13522	FB:FBgn0265140
Drosophila melanogaster	57025	FB:FBgn0265140
Drosophila melanogaster	80332	FB:FBgn0265140
Drosophila melanogaster	110751	FB:FBgn0265140
Danio rerio	181489	ZFIN:ZDB-GENE-070808-1
Danio rerio	368917		DANRE06089
Rattus norvegicus	499285		RATNO16893

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements