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malate dehydrogenase 1

Summary

Gene Symbol

MDH1

Organism

Vicugna pacos (alpaca)

External Links

NCBI Gene: 102533479
KEGG Gene ID: vpc:102533479
PubChem: 102533479

Annotation

Keyword

NAD
Oxidoreductase
Reference proteome
Tricarboxylic acid cycle

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A6I9I4P6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
malate metabolic process	IEA	22301074 30032202
oxaloacetate metabolic process	IEA	30032202
NADH metabolic process	IEA	30032202
tricarboxylic acid cycle	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

primary metabolic process [inference]

tricarboxylic acid cycle

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying 1 entry
GO Term	Evidence Code	PMID
L-malate dehydrogenase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

malate dehydrogenase activity [inference]

L-malate dehydrogenase activity

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

L-malate dehydrogenase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Artiodactyla

Group Name

Lactate/malate dehydrogenase, C-terminal

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 10** entries
Gene Ontology
L-malate dehydrogenase activity
NADH metabolic process
carboxylic acid metabolic process
catalytic activity
malate dehydrogenase activity
malate metabolic process
oxaloacetate metabolic process
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity
tricarboxylic acid cycle

Displaying **all 8** entries
InterPro
L-lactate/malate dehydrogenase
Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Lactate/malate dehydrogenase, C-terminal
Lactate/malate dehydrogenase, N-terminal
Malate dehydrogenase, NAD-dependent, cytosolic
Malate dehydrogenase, active site
Malate dehydrogenase, type 2
NAD(P)-binding domain superfamily

KEGG BRITE Database

Orthology

K00025

Name

malate dehydrogenase [EC:1.1.1.37]

References

Rhea

RHEA:21432

(S)-malate + NAD⁺

H⁺ + oxaloacetate + NADH

Enzyme

PMID

Ortholog

Displaying entries **1 - 10** of **126** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	4190		HUMAN62934
Mus musculus	17449		MOUSE07454
Rattus norvegicus	24551		RATNO08533
Danio rerio	335715		DANRE12103
Sus scrofa	396894	9823_0:00112d	PIGXX21951
Danio rerio	399662		DANRE18223
Pan troglodytes	459271		PANTR27718
Felis catus	493924		FELCA06467
Bos taurus	535182	9913_0:002250	BOVIN02635
Macaca mulatta	694703		MACMU07569

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements