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cyclin dependent kinase inhibitor 1B

Summary

Gene Symbol

CDKN1B

Organism

Homo sapiens (human)

External Links

NCBI Gene

1027

PubChem

1027

Alliance of Genome Resources

HGNC:1785

JoGo

CDKN1B

TogoVar

CDKN1B

Annotation

Keyword

3D-structure
Cell cycle
Cytoplasm
Direct protein sequencing
Endosome
Nucleus
Phosphoprotein
Protein kinase inhibitor
Proteomics identification
Reference proteome
Tumor suppressor
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P46527	Cyclin-dependent kinase inhibitor p27 p27Kip1
Q6I9V6	Cyclin-dependent kinase inhibitor p27 p27Kip1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 50 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	IEA
negative regulation of cell population proliferation	IMP	19838216
response to xenobiotic stimulus	IEA
response to glucose	IEA
negative regulation of cell growth	IDA	10208428

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

cellular senescence

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

epithelial cell apoptotic process

autophagic cell death

cell population proliferation [inference]

epithelial cell proliferation [inference]

epithelial cell proliferation involved in prostate gland development

cell cycle process [inference]

cell cycle phase transition [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cell cycle G1/S phase transition [inference]

G1/S transition of mitotic cell cycle

mitotic cell cycle process [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cellular metabolic process [inference]

cellular senescence

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to antibiotic

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to lithium ion

cellular response to organic substance [inference]

cellular response to organic cyclic compound

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to oxygen-containing compound [inference]

cellular response to lithium ion

cellular response to salt [inference]

cellular response to lithium ion

reproductive process [inference]

epithelial cell proliferation involved in prostate gland development

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

inner ear development

response to stimulus [inference]

response to stress [inference]

response to hypoxia [inference]

cellular response to hypoxia

cellular response to stress [inference]

DNA damage response [inference]

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

cellular response to hypoxia

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia [inference]

cellular response to hypoxia

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone

response to chemical [inference]

response to acid chemical [inference]

response to amino acid

response to xenobiotic stimulus

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

response to organonitrogen compound [inference]

response to amino acid

response to peptide [inference]

response to peptide hormone

response to organic cyclic compound [inference]

response to lipid [inference]

response to estradiol

cellular response to organic substance [inference]

cellular response to organic cyclic compound

response to inorganic substance [inference]

response to metal ion [inference]

response to lithium ion [inference]

cellular response to lithium ion

response to cadmium ion

cellular response to metal ion [inference]

cellular response to lithium ion

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to lithium ion

response to antibiotic [inference]

cellular response to antibiotic

cellular response to chemical stimulus [inference]

cellular response to antibiotic

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to lithium ion

cellular response to organic substance [inference]

cellular response to organic cyclic compound

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to oxygen-containing compound [inference]

cellular response to lithium ion

cellular response to salt [inference]

cellular response to lithium ion

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to amino acid

response to peptide [inference]

response to peptide hormone

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

response to lithium ion [inference]

cellular response to lithium ion

response to peptide [inference]

response to peptide hormone

cellular response to oxygen-containing compound [inference]

cellular response to lithium ion

response to salt [inference]

response to lithium ion [inference]

cellular response to lithium ion

cellular response to salt [inference]

cellular response to lithium ion

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to antibiotic

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to lithium ion

cellular response to organic substance [inference]

cellular response to organic cyclic compound

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to oxygen-containing compound [inference]

cellular response to lithium ion

cellular response to salt [inference]

cellular response to lithium ion

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of kinase activity [inference]

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of growth [inference]

regulation of cell growth [inference]

negative regulation of cell growth

negative regulation of growth [inference]

negative regulation of cell growth

negative regulation of developmental growth [inference]

negative regulation of cardiac muscle tissue regeneration

regulation of developmental growth [inference]

negative regulation of developmental growth [inference]

negative regulation of cardiac muscle tissue regeneration

regulation of cardiac muscle tissue regeneration [inference]

negative regulation of cardiac muscle tissue regeneration

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of growth [inference]

negative regulation of cell growth

negative regulation of developmental growth [inference]

negative regulation of cardiac muscle tissue regeneration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of smooth muscle cell proliferation [inference]

negative regulation of vascular associated smooth muscle cell proliferation

negative regulation of epithelial cell proliferation

negative regulation of epithelial cell proliferation involved in prostate gland development

negative regulation of cell growth

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of epithelial cell apoptotic process

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of mitotic cell cycle

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of developmental process [inference]

negative regulation of developmental growth [inference]

negative regulation of cardiac muscle tissue regeneration

negative regulation of epithelial cell proliferation involved in prostate gland development

negative regulation of multicellular organismal process [inference]

negative regulation of epithelial cell proliferation involved in prostate gland development

negative regulation of reproductive process [inference]

negative regulation of epithelial cell proliferation involved in prostate gland development

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of lens fiber cell differentiation

regulation of developmental growth [inference]

negative regulation of developmental growth [inference]

negative regulation of cardiac muscle tissue regeneration

regulation of cardiac muscle tissue regeneration [inference]

negative regulation of cardiac muscle tissue regeneration

negative regulation of developmental process [inference]

negative regulation of developmental growth [inference]

negative regulation of cardiac muscle tissue regeneration

negative regulation of epithelial cell proliferation involved in prostate gland development

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of lens fiber cell differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

negative regulation of DNA-templated transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of kinase activity [inference]

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

regulation of microtubule polymerization [inference]

positive regulation of microtubule polymerization

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

negative regulation of cell population proliferation

negative regulation of smooth muscle cell proliferation [inference]

negative regulation of vascular associated smooth muscle cell proliferation

negative regulation of epithelial cell proliferation

negative regulation of epithelial cell proliferation involved in prostate gland development

regulation of smooth muscle cell proliferation [inference]

negative regulation of smooth muscle cell proliferation [inference]

negative regulation of vascular associated smooth muscle cell proliferation

regulation of vascular associated smooth muscle cell proliferation [inference]

negative regulation of vascular associated smooth muscle cell proliferation

regulation of epithelial cell proliferation [inference]

negative regulation of epithelial cell proliferation

negative regulation of epithelial cell proliferation involved in prostate gland development

regulation of epithelial cell proliferation involved in prostate gland development [inference]

negative regulation of epithelial cell proliferation involved in prostate gland development

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of epithelial cell apoptotic process

regulation of epithelial cell apoptotic process [inference]

negative regulation of epithelial cell apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of epithelial cell apoptotic process

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of lens fiber cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of smooth muscle cell proliferation [inference]

negative regulation of vascular associated smooth muscle cell proliferation

negative regulation of epithelial cell proliferation

negative regulation of epithelial cell proliferation involved in prostate gland development

negative regulation of cell growth

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of epithelial cell apoptotic process

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of mitotic cell cycle

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

regulation of cellular component organization [inference]

regulation of cell growth [inference]

negative regulation of cell growth

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

regulation of cytoskeleton organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

regulation of microtubule polymerization [inference]

positive regulation of microtubule polymerization

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization

regulation of supramolecular fiber organization [inference]

regulation of microtubule polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization

regulation of cell cycle

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

regulation of mitotic cell cycle phase transition [inference]

regulation of exit from mitosis

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

regulation of G1/S transition of mitotic cell cycle

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

regulation of mitotic cell cycle phase transition [inference]

regulation of exit from mitosis

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

regulation of G1/S transition of mitotic cell cycle

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

regulation of cell cycle G1/S phase transition

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

regulation of G1/S transition of mitotic cell cycle

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of mitotic cell cycle

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle [inference]

mitotic G1/S transition checkpoint signaling [inference]

mitotic G1 DNA damage checkpoint signaling [inference]

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cell motility [inference]

regulation of cell migration

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of epithelial cell proliferation involved in prostate gland development

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of lens fiber cell differentiation

regulation of reproductive process [inference]

regulation of epithelial cell proliferation involved in prostate gland development [inference]

negative regulation of epithelial cell proliferation involved in prostate gland development

negative regulation of reproductive process [inference]

negative regulation of epithelial cell proliferation involved in prostate gland development

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of transferase activity [inference]

negative regulation of kinase activity

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of cyclin-dependent protein serine/threonine kinase activity

negative regulation of cyclin-dependent protein kinase activity

negative regulation of cyclin-dependent protein serine/threonine kinase activity

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
nucleus	IDA	11800646 12093740
nucleus	IBA
nucleoplasm	TAS
nucleoplasm	IDA
cytoplasm	IDA	12093740

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

ubiquitin ligase complex [inference]

cullin-RING ubiquitin ligase complex [inference]

Cul4-RING E3 ubiquitin ligase complex [inference]

Cul4A-RING E3 ubiquitin ligase complex

catalytic complex [inference]

transferase complex [inference]

ubiquitin ligase complex [inference]

cullin-RING ubiquitin ligase complex [inference]

Cul4-RING E3 ubiquitin ligase complex [inference]

Cul4A-RING E3 ubiquitin ligase complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

cytosol

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
protein kinase inhibitor activity	IMP	8684460
cyclin-dependent protein serine/threonine kinase inhibitor activity	TAS
cyclin-dependent protein serine/threonine kinase inhibitor activity	IDA	10918569 28666995 8033212
cyclin-dependent protein serine/threonine kinase inhibitor activity	IBA
protein binding	IPI	11961546 12082530 12093740 15024385 15057270 15480426 15652749 15890360 16189514 16209941 16289477 16326706 16431923 17053782 17254966 17254967 17418410 17698606 18177895 18593906 18692475 18805092 19470470 20596027 21423214 21423803 22632967 22770219 23455922 23543736 23602409 23602568 24358021 25241761 25852190 25910212 26496610 26775844 28425505 28514442 29997244 31515488 32296183 32707033 32814053 33961781 34591612 34591642 35271311 8684460 8756624 9106657 9840943

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

phosphatase binding [inference]

protein phosphatase binding

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

cyclin binding

heat shock protein binding [inference]

Hsp70 protein binding

protein-folding chaperone binding

Hsp70 protein binding

protein-containing complex binding

molecular adaptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

kinase inhibitor activity [inference]

protein kinase inhibitor activity

protein serine/threonine kinase inhibitor activity [inference]

cyclin-dependent protein serine/threonine kinase inhibitor activity

enzyme activator activity [inference]

ubiquitin-protein transferase activator activity [inference]

ubiquitin ligase activator activity

kinase regulator activity [inference]

kinase inhibitor activity [inference]

protein kinase inhibitor activity

protein serine/threonine kinase inhibitor activity [inference]

cyclin-dependent protein serine/threonine kinase inhibitor activity

protein kinase regulator activity [inference]

protein kinase inhibitor activity

protein serine/threonine kinase inhibitor activity [inference]

cyclin-dependent protein serine/threonine kinase inhibitor activity

cyclin-dependent protein serine/threonine kinase regulator activity [inference]

cyclin-dependent protein serine/threonine kinase inhibitor activity

cyclin-dependent protein kinase activating kinase regulator activity

ubiquitin-protein transferase regulator activity [inference]

ubiquitin-protein transferase activator activity [inference]

ubiquitin ligase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

ubiquitin-protein transferase activator activity [inference]

ubiquitin ligase activator activity

molecular function inhibitor activity

enzyme inhibitor activity [inference]

kinase inhibitor activity [inference]

protein kinase inhibitor activity

protein serine/threonine kinase inhibitor activity [inference]

cyclin-dependent protein serine/threonine kinase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cyclin dependent kinase inhibitor 1B

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
G1/S transition of mitotic cell cycle
cyclin-dependent protein serine/threonine kinase inhibitor activity
negative regulation of cell population proliferation
negative regulation of mitotic cell cycle
protein kinase inhibitor activity
protein-folding chaperone binding

Displaying **all 2** entries
InterPro
Cyclin-dependent kinase inhibitor domain superfamily
Cyclin-dependent kinase inhibitor domain

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0050908	myelodysplastic syndrome	Alliance of Genome Resources
DOID:0080137	multiple endocrine neoplasia type 4	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:9119	acute myeloid leukemia	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements