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MIRAGE
acute myeloid leukemia
Summary
- Synonym
-
- AML - acute Myeloid Leukemia
- Leukemia, Myelocytic, acute
- acute myeloblastic leukaemia
- acute myeloblastic leukemia
- acute myelogenous leukaemia
- acute myelogenous leukemia
- acute myeloid leukaemia
- Definition
- A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.
- Super Class
- myeloid leukemia
External Links
- Disease Ontology
- DOID:9119
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- GARD
- MGI genotype (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 10 | NAT2 | N-acetyltransferase 2 | |
| 25 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | |
| 355 | FAS | Fas cell surface death receptor | |
| 648 | BMI1 | BMI1 proto-oncogene, polycomb ring finger | |
| 861 | RUNX1 | RUNX family transcription factor 1 | |
| 867 | CBL | Cbl proto-oncogene | |
| 999 | CDH1 | cadherin 1 | |
| 1027 | CDKN1B | cyclin dependent kinase inhibitor 1B | |
| 1387 | CREBBP | CREB binding protein | |
| 1437 | CSF2 | colony stimulating factor 2 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O14746 | Telomerase reverse transcriptase | |
| O15553 | Pyrin | |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | |
| P00519 | Tyrosine-protein kinase ABL1 | |
| P01111 | GTPase NRas | |
| P01116 | GTPase KRas | |
| P01583 | Interleukin-1 alpha | |
| P01920 | HLA class II histocompatibility antigen, DQ beta 1 chain | |
| P04141 | Granulocyte-macrophage colony-stimulating factor | |
| P04179 | Superoxide dismutase [Mn], mitochondrial |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P45481 | Histone lysine acetyltransferase CREBBP | |
| P55200 | Histone-lysine N-methyltransferase 2A | |
| P59598 | Polycomb group protein ASXL1 | |
| Q00342 | Receptor-type tyrosine-protein kinase FLT3 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P49687 | Nucleoporin NUP145 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0001442 | Typified by somatic mosaicism |
| HP:0004808 | Acute myeloid leukemia |
