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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Isocitrate dehydrogenase [NADP] cytoplasmic
Summary
- UniProt ID
- O75874
- Gene Symbol
-
- IDH1
- PICD
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Cytoplasm
- Direct protein sequencing
- Glyoxylate bypass
- Magnesium
- Manganese
- Metal-binding
- NADP
- Oxidoreductase
- Peroxisome
- Phosphoprotein
- Reference proteome
- Tricarboxylic acid cycle
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| cytoplasm |
| extracellular exosome |
| tertiary granule lumen |
| secretory granule lumen |
| mitochondrion |
| peroxisome |
| cytosol |
| peroxisomal matrix |
| ficolin-1-rich granule lumen |
Sequence
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Glycosylation Sites
G71784JC
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate | Homo sapiens |
| NADPH regeneration | Homo sapiens |
| NFE2L2 regulating TCA cycle genes | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| Peroxisomal protein import | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:184 | bone cancer | |
| DOID:0014667 | disease of metabolism | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050486 | exanthem | |
| DOID:0050573 | 2-hydroxyglutaric aciduria | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050646 | distal arthrogryposis | |
| DOID:0050745 | diffuse large B-cell lymphoma | |
| DOID:0050749 | peripheral T-cell lymphoma | |
| DOID:0050754 | ataxia with oculomotor apraxia type 1 |
