autoimmune disease

Summary
Synonym
  • autoimmune hypersensitivity disease
  • hypersensitivity reaction type II disease
Definition
An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.
Super Class
primary immunodeficiency disease
Disease Ontology
DOID:417
UMLS
MGI genotype (from TogoID)
Related Genes
Displaying all 7 entries
Gene ID Gene Symbol Description Source
142 PARP1 poly(ADP-ribose) polymerase 1
3117 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
3119 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3417 IDH1 isocitrate dehydrogenase (NADP(+)) 1
54414 SIAE sialic acid acetylesterase
64127 NOD2 nucleotide binding oligomerization domain containing 2
Displaying all 2 entries
Gene ID Gene Symbol Description Source
17470 Cd200 CD200 molecule
56696 Gpr132 G protein-coupled receptor 132

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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