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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Nucleotide-binding oligomerization domain-containing protein 2
Summary
- UniProt ID
- Q9HC29
- Gene Symbol
-
- NOD2
- CARD15
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9HC29
- PubChem
- Q9HC29
- The Human Metabolome Database
- HMDBP13949
Annotation
- Keyword
-
- ATP-binding
- Adaptive immunity
- Alternative initiation
- Autophagy
- Cell membrane
- Cytoplasm
- Disease variant
- Glycoprotein
- Innate immunity
- Leucine-rich repeat
- Mitochondrion
- Palmitate
- Reference proteome
- Repeat
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi apparatus |
| cytosol |
| cell surface |
| basolateral plasma membrane |
| cytoplasm |
| mitochondrion |
| cytoskeleton |
| plasma membrane |
| vesicle |
| protein-containing complex |
| GO Term |
|---|
| CARD domain binding |
| actin binding |
| ATP binding |
| enzyme binding |
| protein kinase binding |
| Hsp70 protein binding |
| ubiquitin binding |
| ADP binding |
| protein-containing complex binding |
| Hsp90 protein binding |
Sequence
MGEEGGSASHDEEERASVLLGHSPGCEMCSQEAFQAQRSQLVELLVSGSLEGFESVLDWLLSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLHGCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECALHCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRGNTFSLEEVDKLGCRDTRLLL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 777 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-1 signaling | Homo sapiens |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | Homo sapiens |
| NOD1/2 Signaling Pathway | Homo sapiens |
| Ovarian tumor domain proteases | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
| TAK1-dependent IKK and NF-kappa-B activation | Homo sapiens |
| activated TAK1 mediates p38 MAPK activation | Homo sapiens |
