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Standards Ontologies Notations
graft-versus-host disease

Summary
Synonym
  • GvHD
  • graft versus host disease
Definition
An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.
Super Class
immune system disease
Disease Ontology
DOID:0081267
Mondo Disease Ontology
MeSH
ORDO
OMIM
Related Genes
Displaying entries 1 - 10 of 33 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
337 APOA4 apolipoprotein A4
355 FAS Fas cell surface death receptor
356 FASLG Fas ligand
1493 CTLA4 cytotoxic T-lymphocyte associated protein 4
2152 F3 coagulation factor III, tissue factor
2214 FCGR3A Fc gamma receptor IIIa
3082 HGF hepatocyte growth factor
3105 HLA-A major histocompatibility complex, class I, A
3106 HLA-B major histocompatibility complex, class I, B
Displaying entries 1 - 10 of 30 in total
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
12477 Ctla4 cytotoxic T-lymphocyte-associated protein 4
14066 F3 coagulation factor III
14102 Fas Fas cell surface death receptor
14103 Fasl Fas ligand
14964 H2-D1 histocompatibility 2, D region locus 1
14972 H2-K1 histocompatibility 2, K1, K region
15006 H2-Q1 histocompatibility 2, Q region locus 1
15007 H2-Q10 histocompatibility 2, Q region locus 10
15015 H2-Q4 histocompatibility 2, Q region locus 4
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
24446 Hgf hepatocyte growth factor
24472 Hspa1a heat shock protein family A (Hsp70) member 1A
24493 Il1a interleukin 1 alpha
24628 Pdgfb platelet derived growth factor subunit B
24842 Tp53 tumor protein p53
25325 Il10 interleukin 10
25385 Faslg Fas ligand
25712 Ifng interferon gamma
29259 Sell selectin L
29436 Tfpi tissue factor pathway inhibitor
Displaying 1 entry
Gene ID Gene Symbol Description Source
41840 Hsc70-4 Heat shock protein 70 cognate 4
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
387303 gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
447881 gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
563897 gbgt1l5 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 5
566487 gbgt1l2 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 2
100005565 gbgt1l8 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 8
100005704 gbgt1l9 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 9
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
495825 abo.3.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog Xenopus laevis (African clawed frog)
549437 abo.3 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 Xenopus tropicalis (tropical clawed frog)
549858 abo.2 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 Xenopus tropicalis (tropical clawed frog)
550054 abo ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 Xenopus tropicalis (tropical clawed frog)
100497509 abo.4 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 Xenopus tropicalis (tropical clawed frog)
108698211 abo.2.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 L homeolog Xenopus laevis (African clawed frog)
108698863 abo.4.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 L homeolog Xenopus laevis (African clawed frog)
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024