ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

Summary
Gene Symbol
  • ABO
Aliases
  • A3GALNT
  • A3GALT1
Organism
Homo sapiens (human)
NCBI Gene
28
GGDB ID
HGNC
79
mRNA
map
  • 9q34.1-q34.2
Protein
OMIM
KEGG Gene ID
hsa:28
PubChem
28
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Blood group antigen
  • Direct protein sequencing
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Manganese
  • Metal-binding
  • Reference proteome
  • Secreted
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
A0A089QDC1
P16442
  • Fucosylglycoprotein 3-alpha-galactosyltransferase
  • Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase
  • Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase
  • Glycoprotein-fucosylgalactoside alpha-galactosyltransferase
  • Histo-blood group A transferase
  • Histo-blood group B transferase
  • NAGAT
Gene Ontology (GO)
Displaying all 3 entries
GO Term Evidence Code PMID
protein glycosylation
carbohydrate metabolic process
lipid glycosylation
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
A transferase
Functional Category
  • O: Posttranslational modification, protein turnover, chaperones
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
GlycoGene Database (GGDB)
GGDB ID
gg200
Gene Symbol
  • ABO
Reactions
Displaying all 2 entries
Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
UDP-Gal
G00068MO
R
G47548GA
R
UDP-Gal
G64904FE
O-glycan Synthesis
G14646AF
O-glycan Synthesis
Displaying entries 1 - 5 of 30 in total
Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
UDP-Gal
G14380OJ
O-glycan Synthesis
G43946PN
O-glycan Synthesis
UDP-Gal
G00068MO
R
G47548GA
R
UDP-Gal
G64904FE
O-glycan Synthesis
G14646AF
O-glycan Synthesis
UDP-Gal
G16673GG
R
G19620VP
R
UDP-Gal
G38351JR
O-glycan Synthesis
G28599FB
O-glycan Synthesis
Displaying entries 1 - 5 of 6 in total
Donor Acceptor Reducing terminal(Acceptor) Reference
UDP-Gal
G32723SL
O-glycan Synthesis
UDP-Gal
G19749DC
O-glycan Synthesis
UDP-Gal
G11647UD
O-glycan Synthesis
UDP-GalNAc
G19749DC
O-glycan Synthesis
UDP-GalNAc
G32723SL
O-glycan Synthesis
Orthologous Gene
Displaying all 2 entries
Species Protein mRNA
Rattus norvegicus NP_075582 NM_023094
Mus musculus NP_109643 NM_030718
Disease
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP006775
Gene Name
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024