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MIRAGE
hepatocyte growth factor
Summary
- Gene Symbol
-
- HGF
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Growth factor
- Kringle
- Non-syndromic deafness
- Pyrrolidone carboxylic acid
- Reference proteome
- Repeat
- Serine protease homolog
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P14210 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitotic cell cycle | ||
| cell morphogenesis | ||
| epithelial to mesenchymal transition | ||
| liver development | ||
| proteolysis |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| membrane | ||
| platelet alpha granule lumen |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| endopeptidase activity | ||
| serine-type endopeptidase activity | ||
| signaling receptor binding | ||
| protein binding | ||
| growth factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- hepatocyte growth factor
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| proteolysis |
| serine-type endopeptidase activity |
| signaling receptor binding |
| InterPro |
|---|
| Kringle superfamily |
| Kringle, conserved site |
| Kringle-like fold |
| Kringle |
| PAN/Apple domain |
| Serine proteases, trypsin domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050852 | limb ischemia | |
| DOID:0081267 | graft-versus-host disease | |
| DOID:0110497 | autosomal recessive nonsyndromic deafness 39 | |
| DOID:10126 | keratoconus | |
| DOID:10763 | hypertension | |
| DOID:11446 | sciatic neuropathy | |
| DOID:11830 | myopia | |
| DOID:12306 | vitiligo | |
| DOID:13550 | angle-closure glaucoma | |
| DOID:2741 | bilirubin metabolic disorder |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3082 | Xenbase:XB-GENE-999992 | ||
| 15234 | Xenbase:XB-GENE-999992 | MOUSE44721 | |
| 24446 | Xenbase:XB-GENE-999992 | RATNO30163 | |
| 282879 | BOVIN27851 | ||
| 403441 | CANLF05577 | ||
| 443075 | SHEEP15394 | ||
| 463503 | PANTR40638 | ||
| 493705 | FELCA05333 | ||
| 493781 | DANRE32694 | ||
| 708316 | MACMU32274 |
