angle-closure glaucoma

Summary
Synonym
  • ACG - Angle-closure glaucoma
  • Angle Closure Glaucoma
  • Closed angle glaucoma
  • Narrow cleft glaucoma
  • primary open-angle glaucoma with narrow angles
Definition
A glaucoma characterized by closure of the anterior chamber angle such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Angle-closure glaucoma has_symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Angle closure glaucoma can be caused by anatomically narrow angle, injury to the trabecular meshwork, and injuries to the anterior chamber, such as neovascularization and uveitis.
Super Class
glaucoma
External Links
Disease Ontology
DOID:13550
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying all 10 entries
Gene ID Gene Symbol Description Source
847 CAT catalase
1103 CHAT choline O-acetyltransferase
1109 AKR1C4 aldo-keto reductase family 1 member C4
1545 CYP1B1 cytochrome P450 family 1 subfamily B member 1
1555 CYP2B6 cytochrome P450 family 2 subfamily B member 6
1634 DCN decorin
4907 NT5E 5'-nucleotidase ecto
4968 OGG1 8-oxoguanine DNA glycosylase
7021 TFAP2B transcription factor AP-2 beta
8818 DPM2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory
Displaying 1 entry
Gene ID Gene Symbol Description Source
21419 Tfap2b transcription factor AP-2 beta

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024