NOD1/2 Signaling Pathway

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMOPAMP:NOD oligomer:RIP2:NEMOK63polyUbNOD1NOD1:iE-DAPiE-DAPNOD2MDP:NOD2MDPNOD1:iE-DAP oligomerMDP:NOD2 oligomerRIP2PAMP:NOD oligomer:RIP2PAMP:NOD oligomerNEMOPAMP:NOD oligomer:RIP2:K63-Ub-K285-NEMOTAK1 complexPAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complexPAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complexMKK6ADPp-S207,T211-MKK6ATPLong prodomain caspasesNOD1:iE-DAP:Long prodomain caspasesCARD9PAMP:NOD oligomer:RIP2:CARD9Phospho-p38 MAPKp38 MAPKAAMPAAMP:NOD2IKK complexp-S177,S181-IKKB:IKKA:NEMO
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025