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Caspase-9

Summary

UniProt ID

P55211

Gene Symbol

CASP9
MCH6

Organism

Homo sapiens (human)

External Links

GlyGen: P55211
PubChem: P55211
The O-GlcNAc Database: P55211

Annotation

Keyword

3D-structure
Alternative splicing
Apoptosis
Phosphoprotein
Reference proteome
Thiol protease
Zymogen

Gene Ontology (GO)

Displaying entries **1 - 10** of 24 in total

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GO Term
response to hypoxia
DNA damage response
cellular response to UV
response to ischemia
kidney development
apoptotic process
protein processing
leukocyte apoptotic process
platelet formation
response to estradiol

Displaying **all 7** entries
GO Term
apoptosome
mitochondrion
cytosol
caspase complex
nucleus
cytoplasm
protein-containing complex

Displaying **all 8** entries
GO Term
enzyme activator activity
peptidase activity
protein kinase binding
SH3 domain binding
identical protein binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity
cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Annotation information from UniProt.

Sequence

MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
AKT phosphorylates targets in the cytosol	Homo sapiens
Activation of caspases through apoptosome-mediated cleavage	Homo sapiens
Constitutive Signaling by AKT1 E17K in Cancer	Homo sapiens
Formation of apoptosome	Homo sapiens
Ligand-independent caspase activation via DCC	Homo sapiens
NOD1/2 Signaling Pathway	Homo sapiens
Regulation of the apoptosome activity	Homo sapiens
SMAC (DIABLO) binds to IAPs	Homo sapiens
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	Homo sapiens