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glioblastoma
Summary
- Synonym
-
- GBM
- adult glioblastoma multiforme
- glioblastoma multiforme
- grade IV adult Astrocytic tumor
- primary glioblastoma multiforme
- spongioblastoma multiforme
- Definition
- A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
- Super Class
- malignant astrocytoma
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 575 | ADGRB1 | adhesion G protein-coupled receptor B1 | |
| 1755 | DMBT1 | deleted in malignant brain tumors 1 | |
| 1950 | EGF | epidermal growth factor | |
| 2146 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | |
| 2323 | FLT3LG | fms related receptor tyrosine kinase 3 ligand | |
| 3417 | IDH1 | isocitrate dehydrogenase (NADP(+)) 1 | |
| 3791 | KDR | kinase insert domain receptor | |
| 4193 | MDM2 | MDM2 proto-oncogene | |
| 4255 | MGMT | O-6-methylguanine-DNA methyltransferase | |
| 4318 | MMP9 | matrix metallopeptidase 9 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P02340 | Cellular tumor antigen p53 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q6P734 | Plasma protease C1 inhibitor |
