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Cellular tumor antigen p53

Summary

UniProt ID

P02340

Gene Symbol

Tp53
P53
Trp53

Organism

Mus musculus (house mouse)

External Links

GlyGen: P02340
PubChem: P02340
The O-GlcNAc Database: P02340

Annotation

Keyword

3D-structure
Acetylation
Activator
Apoptosis
Biological rhythms
Cell cycle
Cytoskeleton
DNA-binding
Disease variant
Endoplasmic reticulum
Isopeptide bond
Metal-binding
Methylation
Mitochondrion
Necrosis
Nucleus
Phosphoprotein
Reference proteome
Repressor
Transcription regulation
Tumor suppressor
Ubl conjugation
Zinc

Gene Ontology (GO)

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GO Term
in utero embryonic development
somitogenesis
T cell proliferation involved in immune response
positive regulation of leukocyte migration
apoptotic process
response to oxidative stress
spermatogenesis
regulation of mitotic cell cycle
gastrulation
neuroblast proliferation

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GO Term
nucleus
nucleolus
cytoplasm
germ cell nucleus
nuclear matrix
PML body
transcription repressor complex
chromatin
mitochondrion
mitochondrial matrix

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GO Term
ubiquitin protein ligase binding
identical protein binding
protein heterodimerization activity
RNA polymerase II transcription regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription repressor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
sequence-specific DNA binding
transmembrane transporter binding

Annotation information from UniProt.

Sequence

MTAMEESQSDISLELPLSQETFSGLWKLLPPEDILPSPHCMDDLLLPQDVEEFFEGPSEALRVSGAPAAQDPVTETPGPVAPAPATPWPLSSFVPSQKTYQGNYGFHLGFLQSGTAKSVMCTYSPPLNKLFCQLAKTCPVQLWVSATPPAGSRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNLYPEYLEDRQTFRHSVVVPYEPPEAGSEYTTIHYKYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKKEVLCPELPPGSAKRALPTCTSASPPQKKKPLDGEYFTLKIRGRKRFEMFRELNEALELKDAHATEESGDSRAHSSYLKTKKGQSTSRHKKTMVKKVGPDSD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Autodegradation of the E3 ubiquitin ligase COP1	Mus musculus
DNA Damage/Telomere Stress Induced Senescence	Mus musculus
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	Mus musculus
G2/M Checkpoints	Mus musculus
G2/M DNA damage checkpoint	Mus musculus
Oncogene Induced Senescence	Mus musculus
Ovarian tumor domain proteases	Mus musculus
Oxidative Stress Induced Senescence	Mus musculus
PI5P Regulates TP53 Acetylation	Mus musculus
PKR-mediated signaling	Mus musculus