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enhancer of zeste 2 polycomb repressive complex 2 subunit

Summary

Gene Symbol

EZH2

Organism

Homo sapiens (human)

External Links

NCBI Gene

2146

PubChem

2146

Alliance of Genome Resources

HGNC:3527

Annotation

Keyword

3D-structure
Alternative splicing
Biological rhythms
Chromatin regulator
Disease variant
Glycoprotein
Isopeptide bond
Methyltransferase
Nucleus
Phosphoprotein
Reference proteome
Repressor
S-adenosyl-L-methionine
Transcription regulation
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q15910	ENX-1 Enhancer of zeste homolog 2 Lysine N-methyltransferase 6
A0A090N8E9
S4S3R8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 52 in total

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GO Term	Evidence Code	PMID
G1/S transition of mitotic cell cycle	IEA
negative regulation of transcription by RNA polymerase II	IDA	20154697
chromatin organization	TAS
DNA methylation-dependent heterochromatin formation	IEA
regulation of transcription, DNA-templated	TAS

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

methylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process

macromolecule modification [inference]

protein modification process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, GABAergic

cell cycle process [inference]

cell cycle phase transition [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cell cycle G1/S phase transition [inference]

G1/S transition of mitotic cell cycle

G1 to G0 transition

mitotic cell cycle process [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

keratinocyte differentiation

stem cell differentiation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromatin

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to antibiotic [inference]

cellular response to trichostatin A

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to trichostatin A

cellular response to organonitrogen compound [inference]

cellular response to trichostatin A

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to trichostatin A

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to trichostatin A

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization

chromatin remodeling [inference]

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

heterochromatin organization [inference]

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

system process [inference]

muscle system process [inference]

muscle hypertrophy [inference]

muscle hypertrophy in response to stress [inference]

cardiac muscle hypertrophy in response to stress

striated muscle hypertrophy [inference]

cardiac muscle hypertrophy [inference]

cardiac muscle hypertrophy in response to stress

muscle adaptation [inference]

muscle hypertrophy in response to stress [inference]

cardiac muscle hypertrophy in response to stress

striated muscle adaptation [inference]

cardiac muscle adaptation [inference]

cardiac muscle hypertrophy in response to stress

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

hepatocyte homeostasis

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

animal organ regeneration [inference]

liver regeneration

animal organ development [inference]

animal organ regeneration [inference]

liver regeneration

gland development [inference]

liver development [inference]

liver regeneration

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

keratinocyte differentiation

stem cell differentiation

maintenance of cell number [inference]

skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

hepatocyte homeostasis

rhythmic process

response to stimulus [inference]

response to stress [inference]

muscle hypertrophy in response to stress [inference]

cardiac muscle hypertrophy in response to stress

response to oxidative stress [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to trichostatin A

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to trichostatin A [inference]

cellular response to trichostatin A

cellular response to organonitrogen compound [inference]

cellular response to trichostatin A

response to organic cyclic compound [inference]

response to estradiol

response to trichostatin A [inference]

cellular response to trichostatin A

cellular response to organic cyclic compound [inference]

cellular response to trichostatin A

response to lipid [inference]

response to estradiol

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to trichostatin A

cellular response to organonitrogen compound [inference]

cellular response to trichostatin A

response to tetrachloromethane

response to inorganic substance [inference]

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

response to antibiotic [inference]

response to trichostatin A [inference]

cellular response to trichostatin A

cellular response to antibiotic [inference]

cellular response to trichostatin A

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to antibiotic [inference]

cellular response to trichostatin A

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to trichostatin A

cellular response to organonitrogen compound [inference]

cellular response to trichostatin A

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to trichostatin A

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to trichostatin A

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to trichostatin A [inference]

cellular response to trichostatin A

cellular response to organonitrogen compound [inference]

cellular response to trichostatin A

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to trichostatin A

response to oxygen-containing compound [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

response to estradiol

response to trichostatin A [inference]

cellular response to trichostatin A

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to trichostatin A

muscle adaptation [inference]

muscle hypertrophy in response to stress [inference]

cardiac muscle hypertrophy in response to stress

striated muscle adaptation [inference]

cardiac muscle adaptation [inference]

cardiac muscle hypertrophy in response to stress

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to antibiotic [inference]

cellular response to trichostatin A

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to trichostatin A

cellular response to organonitrogen compound [inference]

cellular response to trichostatin A

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to trichostatin A

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to trichostatin A

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromatin

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromatin

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

negative regulation of signal transduction [inference]

negative regulation of retinoic acid receptor signaling pathway

regulation of retinoic acid receptor signaling pathway [inference]

negative regulation of retinoic acid receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of retinoic acid receptor signaling pathway

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, GABAergic

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of circadian rhythm

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of cell cycle G1/S phase transition

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of dendrite development

positive regulation of multicellular organismal process [inference]

positive regulation of epithelial to mesenchymal transition

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of retinoic acid receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of retinoic acid receptor signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation

negative regulation of stem cell differentiation

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of retinoic acid receptor signaling pathway

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation

negative regulation of stem cell differentiation

negative regulation of epidermis development [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of keratinocyte differentiation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

negative regulation of signal transduction [inference]

negative regulation of retinoic acid receptor signaling pathway

regulation of retinoic acid receptor signaling pathway [inference]

negative regulation of retinoic acid receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of retinoic acid receptor signaling pathway

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition

regulation of epithelial cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of epidermal cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of keratinocyte differentiation [inference]

negative regulation of keratinocyte differentiation

negative regulation of cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation

negative regulation of stem cell differentiation

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

regulation of muscle cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation

regulation of striated muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation

regulation of cell development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis

regulation of stem cell differentiation [inference]

negative regulation of stem cell differentiation

regulation of epidermis development [inference]

regulation of epidermal cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of keratinocyte differentiation [inference]

negative regulation of keratinocyte differentiation

negative regulation of epidermis development [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of dendrite development [inference]

positive regulation of dendrite development

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation

negative regulation of stem cell differentiation

negative regulation of epidermis development [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of dendrite development

regulation of kidney development

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of epidermal cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of keratinocyte differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

negative regulation of signal transduction [inference]

negative regulation of retinoic acid receptor signaling pathway

regulation of retinoic acid receptor signaling pathway [inference]

negative regulation of retinoic acid receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of retinoic acid receptor signaling pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition

regulation of epithelial cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of epidermal cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of keratinocyte differentiation [inference]

negative regulation of keratinocyte differentiation

negative regulation of cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation

negative regulation of stem cell differentiation

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

regulation of muscle cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation

regulation of striated muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation

regulation of cell development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis

regulation of stem cell differentiation [inference]

negative regulation of stem cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of cell cycle G1/S phase transition

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of retinoic acid receptor signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated heterochromatin formation

negative regulation of gene expression, epigenetic

heterochromatin formation

regulatory ncRNA-mediated heterochromatin formation

facultative heterochromatin formation

DNA methylation-dependent heterochromatin formation

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation

negative regulation of stem cell differentiation

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

regulation of dendrite development [inference]

positive regulation of dendrite development

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of cell cycle G1/S phase transition

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle phase transition [inference]

positive regulation of cell cycle G1/S phase transition

regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle G1/S phase transition [inference]

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition

regulation of G1/S transition of mitotic cell cycle [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of cell cycle G1/S phase transition

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

positive regulation of multicellular organismal process [inference]

positive regulation of epithelial to mesenchymal transition

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of keratinocyte differentiation

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of epidermal cell differentiation [inference]

negative regulation of epidermal cell differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of keratinocyte differentiation [inference]

negative regulation of keratinocyte differentiation

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of hydrolase activity [inference]

regulation of GTPase activity [inference]

positive regulation of GTPase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of MAP kinase activity

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
chromosome, telomeric region	IGI	9214638
chromatin	IDA	19734898
nucleus	IDA	19144645
nucleus	IBA
nucleoplasm	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

chromatin

heterochromatin [inference]

pericentric heterochromatin

nuclear protein-containing complex [inference]

chromatin silencing complex

PcG protein complex [inference]

ESC/E(Z) complex

histone methyltransferase complex [inference]

ESC/E(Z) complex

catalytic complex [inference]

transferase complex [inference]

methyltransferase complex [inference]

histone methyltransferase complex [inference]

ESC/E(Z) complex

cellular anatomical entity [inference]

nucleoplasm

cell junction [inference]

synapse

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

pronucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

pronucleus

intracellular non-membrane-bounded organelle [inference]

chromosome

chromosomal region [inference]

chromosome, telomeric region

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GO Term	Evidence Code	PMID
RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
RNA polymerase II core promoter sequence-specific DNA binding	IEA
transcription corepressor binding	IPI	29628311
chromatin binding	IDA	20154697
chromatin binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K27 methyltransferase activity

histone H3K27 trimethyltransferase activity

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K27 methyltransferase activity

histone H3K27 trimethyltransferase activity

histone methyltransferase activity

histone H3 methyltransferase activity

histone H3K27 methyltransferase activity

histone H3K27 trimethyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K27 methyltransferase activity

histone H3K27 trimethyltransferase activity

catalytic activity, acting on a protein [inference]

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K27 methyltransferase activity

histone H3K27 trimethyltransferase activity

histone methyltransferase activity

histone H3 methyltransferase activity

histone H3K27 methyltransferase activity

histone H3K27 trimethyltransferase activity

histone modifying activity [inference]

histone methyltransferase activity

histone H3 methyltransferase activity

histone H3K27 methyltransferase activity

histone H3K27 trimethyltransferase activity

binding [inference]

protein binding

transcription factor binding [inference]

transcription coregulator binding [inference]

transcription corepressor binding

histone binding

protein-containing complex binding [inference]

chromatin binding

ribonucleoprotein complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

core promoter sequence-specific DNA binding [inference]

RNA polymerase II core promoter sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

core promoter sequence-specific DNA binding [inference]

RNA polymerase II core promoter sequence-specific DNA binding

chromatin DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

core promoter sequence-specific DNA binding [inference]

RNA polymerase II core promoter sequence-specific DNA binding

RNA binding

transcription regulator activity [inference]

transcription coregulator activity [inference]

transcription corepressor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Histone-lysine N-methyltransferase

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
chromatin binding
histone H3K27 methyltransferase activity
histone methyltransferase activity
methylation
transferase activity

Displaying **all 5** entries
InterPro
CXC domain
Histone-lysine N-methyltransferase EZH1/2-like
Pre-SET CXC domain
SET domain superfamily
SET domain

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0050861	colorectal adenocarcinoma	Alliance of Genome Resources
DOID:0050866	oral squamous cell carcinoma	Alliance of Genome Resources
DOID:0050908	myelodysplastic syndrome	Alliance of Genome Resources
DOID:0080188	chronic myelomonocytic leukemia	Alliance of Genome Resources
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:1324	lung cancer	Alliance of Genome Resources
DOID:14731	Weaver syndrome	Alliance of Genome Resources
DOID:3068	glioblastoma	Alliance of Genome Resources
DOID:3347	osteosarcoma	Alliance of Genome Resources
DOID:4947	cholangiocarcinoma	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	2146	Xenbase:XB-GENE-956215
Saccharomyces cerevisiae S288C	7468	SGD:S000003704
Mus musculus	14056	Xenbase:XB-GENE-956215	MOUSE48000
Saccharomyces cerevisiae S288C	29072	SGD:S000003704
Saccharomyces cerevisiae S288C	54904	SGD:S000003704
Saccharomyces cerevisiae S288C	64324	SGD:S000003704
Saccharomyces cerevisiae S288C	235626	SGD:S000003704
Rattus norvegicus	312299		RATNO31350
Canis lupus familiaris	475511		CANLF04399
Macaca mulatta	709075		MACMU32855

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements