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Platelet-derived growth factor receptor beta

Summary

UniProt ID: P09619
Gene Symbol: PDGFRB PDGFR PDGFR1
Gene ID: 5159
Organism: Homo sapiens (human)

External Links

GlyConnect

Platelet-derived growth factor receptor beta

GlyGen

P09619

PubChem

P09619

The Human Metabolome Database

HMDBP01435

RaftProt

P09619

Re-Glyco

P09619

Annotation

Keyword: 3D-structure ATP-binding Alternative splicing Cell membrane Chemotaxis Chromosomal rearrangement Cytoplasmic vesicle Developmental protein Direct protein sequencing Disease variant Disulfide bond Glycoprotein Immunoglobulin domain Lysosome Phosphoprotein Proteomics identification Proto-oncogene Receptor Reference proteome Repeat Signal Transmembrane helix Tyrosine-protein kinase Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 65 in total

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GO Term	Evidence Code	Reference
angiogenesis	IBA	GO_REF
signal transduction	IDA	PMID
cell surface receptor protein tyrosine kinase signaling pathway	IBA	GO_REF
cell surface receptor protein tyrosine kinase signaling pathway	IEA	GO_REF
positive regulation of cell population proliferation	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

vascular endothelial growth factor signaling pathway [inference]

VEGF-activated platelet-derived growth factor receptor signaling pathway [inference]

positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway

platelet-derived growth factor receptor signaling pathway

platelet-derived growth factor receptor-beta signaling pathway

regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

VEGF-activated platelet-derived growth factor receptor signaling pathway [inference]

positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway

metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

cell population proliferation [inference]

cell proliferation involved in kidney development [inference]

glomerular mesangial cell proliferation [inference]

metanephric glomerular mesangial cell proliferation involved in metanephros development

cell proliferation involved in metanephros development [inference]

metanephric glomerular mesangial cell proliferation involved in metanephros development

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

myofibril assembly [inference]

cardiac myofibril assembly

cell motility [inference]

cell migration [inference]

muscle cell migration [inference]

smooth muscle cell migration [inference]

smooth muscle cell chemotaxis

cell migration involved in vasculogenesis

cell chemotaxis

smooth muscle cell chemotaxis

cell migration involved in heart development [inference]

cell migration involved in coronary angiogenesis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

myofibril assembly [inference]

cardiac myofibril assembly

organelle assembly [inference]

membraneless organelle assembly [inference]

myofibril assembly [inference]

cardiac myofibril assembly

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

myofibril assembly [inference]

cardiac myofibril assembly

organelle assembly [inference]

membraneless organelle assembly [inference]

myofibril assembly [inference]

cardiac myofibril assembly

supramolecular fiber organization [inference]

myofibril assembly [inference]

cardiac myofibril assembly

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle adaptation [inference]

smooth muscle adaptation

developmental process [inference]

anatomical structure morphogenesis [inference]

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis [inference]

aorta morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

glomerular capillary formation [inference]

metanephric glomerular capillary formation

cellular component assembly involved in morphogenesis [inference]

myofibril assembly [inference]

cardiac myofibril assembly

anatomical structure development [inference]

system development [inference]

vasculature development [inference]

retina vasculature development in camera-type eye

animal gross anatomical part developmental process [inference]

vasculature development [inference]

retina vasculature development in camera-type eye

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

smooth muscle cell chemotaxis

response to stimulus [inference]

muscle adaptation [inference]

smooth muscle adaptation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

regulation of calcium ion import [inference]

positive regulation of calcium ion import

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of metanephric mesenchymal cell migration [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

regulation of chemotaxis [inference]

positive regulation of chemotaxis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of smooth muscle cell migration [inference]

positive regulation of smooth muscle cell migration

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of metanephric mesenchymal cell migration [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

regulation of metanephric mesenchymal cell migration [inference]

regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

positive regulation of metanephric mesenchymal cell migration [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of metanephric mesenchymal cell migration [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of metanephric mesenchymal cell migration [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of reactive oxygen species metabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of metanephric mesenchymal cell migration [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis

regulation of chemotaxis [inference]

positive regulation of chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

vascular endothelial growth factor signaling pathway [inference]

VEGF-activated platelet-derived growth factor receptor signaling pathway [inference]

positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway

platelet-derived growth factor receptor signaling pathway

platelet-derived growth factor receptor-beta signaling pathway

regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

VEGF-activated platelet-derived growth factor receptor signaling pathway [inference]

positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of reactive oxygen species metabolic process

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species metabolic process

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of smooth muscle cell proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of reactive oxygen species metabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of metanephric mesenchymal cell migration [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization

regulation of nuclear division [inference]

regulation of mitotic nuclear division [inference]

positive regulation of mitotic nuclear division

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic nuclear division [inference]

positive regulation of mitotic nuclear division

regulation of cell cycle process [inference]

regulation of mitotic nuclear division [inference]

positive regulation of mitotic nuclear division

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of smooth muscle cell migration [inference]

positive regulation of smooth muscle cell migration

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of metanephric mesenchymal cell migration [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

regulation of metanephric mesenchymal cell migration [inference]

regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

positive regulation of metanephric mesenchymal cell migration [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of metanephric mesenchymal cell migration [inference]

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
nucleus	ISS	GO_REF
cytoplasm	ISS	GO_REF
cytoplasm	IEA	GO_REF
Golgi apparatus
plasma membrane	TAS	Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

cellular anatomical structure [inference]

cytoplasm

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	Reference
protein kinase activity	IDA	PMID
protein kinase activity	IEA	GO_REF
protein tyrosine kinase activity	IDA	PMID
protein tyrosine kinase activity	IEA	GO_REF GO_REF
platelet activating factor receptor activity	TAS	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity [inference]

platelet-derived growth factor receptor activity

platelet-derived growth factor beta-receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

platelet-derived growth factor receptor activity

platelet-derived growth factor beta-receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity [inference]

platelet-derived growth factor receptor activity

platelet-derived growth factor beta-receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

platelet-derived growth factor receptor activity

platelet-derived growth factor beta-receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity [inference]

platelet-derived growth factor receptor activity

platelet-derived growth factor beta-receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

platelet-derived growth factor receptor activity

platelet-derived growth factor beta-receptor activity

binding [inference]

protein binding [inference]

signaling receptor binding

growth factor receptor binding [inference]

platelet-derived growth factor receptor binding

growth factor binding [inference]

enzyme binding

kinase binding [inference]

protein kinase binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

platelet activating factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

platelet-derived growth factor receptor activity

platelet-derived growth factor beta-receptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

lipase activator activity [inference]

phospholipase activator activity [inference]

phospholipase C activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

lipase activator activity [inference]

phospholipase activator activity [inference]

phospholipase C activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRLPGAMPALALKGELLLLSLLLLLEPQISQGLVVTPPGPELVLNVSSTFVLTCSGSAPVVWERMSQEPPQEMAKAQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLETDERKRLYIFVPDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVALPVPYDHQRGFSGIFEDRSYICKTTIGDREVDSDAYYVYRLQVSSINVSVNAVQTVVRQGENITLMCIVIGNEVVNFEWTYPRKESGRLVEPVTDFLLDMPYHIRSILHIPSAELEDSGTYTCNVTESVNDHQDEKAINITVVESGYVRLLGEVGTLQFAELHRSRTLQVVFEAYPPPTVLWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGHYTMRAFHEDAEVQLSFQLQINVPVRVLELSESHPDSGEQTVRCRGRGMPQPNIIWSACRDLKRCPRELPPTLLGNSSEEESQLETNVTYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRNAVGQDTQEVIVVPHSLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQHHSDKRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSNYMAPYDNYVPSAPERTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQDEPEPEPQLELQVEPEPELEQLPDSGCPAPRAEAEDSFL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 12 in total

1

2

Next ›

Last »
Position	Description	PubMed ID	GlyTouCan ID	Source
45	N-linked (GlcNAc...) asparagine			UniProt GlyGen
89	N-linked (GlcNAc...) asparagine	20534510		UniProt GlyGen
103	N-linked (GlcNAc...) asparagine	20534510		UniProt GlyGen
124				GlyGen
215	N-linked (GlcNAc...) asparagine	20534510 29391424	G48414YA	UniProt GlyGen GlyConnect
230	N-linked (GlcNAc...) asparagine	20534510		UniProt GlyGen
292	N-linked (GlcNAc...) asparagine	20534510		UniProt GlyGen
307	N-linked (GlcNAc...) asparagine	20534510 29391424	G38663NM G52131KU	UniProt GlyGen GlyConnect
354	N-linked (GlcNAc...) asparagine			UniProt GlyGen
371	N-linked (GlcNAc...) asparagine	29391424	G86500WE	UniProt GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Constitutive Signaling by Aberrant PI3K in Cancer	Homo sapiens
Downstream signal transduction	Homo sapiens
PI3K/AKT Signaling	Homo sapiens
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Homo sapiens
RAF/MAP kinase cascade	Homo sapiens
Signaling by PDGF	Homo sapiens

Human Protein Atlas

ENSG00000113721

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Disease

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:2226	myeloproliferative neoplasm	Alliance of Genome Resources
DOID:0080109	infantile myofibromatosis	Alliance of Genome Resources
DOID:0111344	myeloproliferative disorder with eosinophilia	Alliance of Genome Resources
DOID:4450	renal cell carcinoma	Alliance of Genome Resources
DOID:0060230	basal ganglia calcification	Alliance of Genome Resources
DOID:3068	glioblastoma	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements