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acute myeloid leukemia
Summary
- Synonym
-
- AML - acute Myeloid Leukemia
- Leukemia, Myelocytic, acute
- acute myeloblastic leukaemia
- acute myeloblastic leukemia
- acute myelogenous leukaemia
- acute myelogenous leukemia
- acute myeloid leukaemia
- Definition
- A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.
- Super Class
- myeloid leukemia
External Links
- Disease Ontology
- DOID:9119
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- GARD
- MGI genotype (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3078 | CFHR1 | complement factor H related 1 | |
| 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | |
| 3417 | IDH1 | isocitrate dehydrogenase (NADP(+)) 1 | |
| 3418 | IDH2 | isocitrate dehydrogenase (NADP(+)) 2 | |
| 3552 | IL1A | interleukin 1 alpha | |
| 3569 | IL6 | interleukin 6 | |
| 3685 | ITGAV | integrin subunit alpha V | |
| 3690 | ITGB3 | integrin subunit beta 3 | |
| 3815 | KIT | KIT proto-oncogene, receptor tyrosine kinase | |
| 3845 | KRAS | KRAS proto-oncogene, GTPase |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O14746 | Telomerase reverse transcriptase | |
| O15553 | Pyrin | |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | |
| P00519 | Tyrosine-protein kinase ABL1 | |
| P01111 | GTPase NRas | |
| P01116 | GTPase KRas | |
| P01583 | Interleukin-1 alpha | |
| P01920 | HLA class II histocompatibility antigen, DQ beta 1 chain | |
| P04141 | Granulocyte-macrophage colony-stimulating factor | |
| P04179 | Superoxide dismutase [Mn], mitochondrial |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P45481 | Histone lysine acetyltransferase CREBBP | |
| P55200 | Histone-lysine N-methyltransferase 2A | |
| P59598 | Polycomb group protein ASXL1 | |
| Q00342 | Receptor-type tyrosine-protein kinase FLT3 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P49687 | Nucleoporin NUP145 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0001442 | Typified by somatic mosaicism |
| HP:0004808 | Acute myeloid leukemia |
