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Standards Ontologies Notations
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

Summary
Gene Symbol
  • HADHA
Organism
Chlorocebus sabaeus (green monkey)
NCBI Gene
103220642
KEGG Gene ID
csab:103220642
PubChem
103220642
Annotation
Keyword
  • Acetylation
  • Fatty acid metabolism
  • Lyase
  • Multifunctional enzyme
  • NAD
  • Oxidoreductase
  • Reference proteome
Proteins
Displaying 1 entry
UniProt Protein Name
A0A0D9R8Q2
Annotation information from UniProt.
Gene Ontology (GO)
Displaying 1 entry
GO Term Evidence Code PMID
fatty acid beta-oxidation
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Cercopithecoidea
Group Name
trifunctional enzyme subunit alpha, mitochondrial
Functional Category
  • H: Coenzyme transport and metabolism
  • I: Lipid transport and metabolism
  • J: Translation, ribosomal structure and biogenesis
  • Q: Secondary metabolites biosynthesis, transport and catabolism
Displaying all 9 entries
Gene Ontology
3-hydroxyacyl-CoA dehydrogenase activity
NAD+ binding
cardiolipin acyl-chain remodeling
catalytic activity
fatty acid beta-oxidation
fatty acid metabolic process
lyase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity
Displaying all 9 entries
InterPro
3-hydroxyacyl-CoA dehydrogenase, C-terminal
3-hydroxyacyl-CoA dehydrogenase, NAD binding
3-hydroxyacyl-CoA dehydrogenase, conserved site
6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
ClpP/crotonase-like domain superfamily
Enoyl-CoA hydratase/isomerase, conserved site
Enoyl-CoA hydratase/isomerase
Fatty acid oxidation complex, alpha subunit, mitochondrial
NAD(P)-binding domain superfamily
KEGG BRITE Database
Orthology
K07515
Name
enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
References
Rhea

RHEA:76647

(3S)-3-hydroxyadipyl-CoA
H2O + (E)-2,3-didehydroadipoyl-CoA
Enzyme
PMID

RHEA:16105

a (3S)-3-hydroxyacyl-CoA
H2O + a (2E)-enoyl-CoA
Enzyme
PMID

RHEA:20724

a 4-saturated-(3S)-3-hydroxyacyl-CoA
H2O + a (3E)-enoyl-CoA
Enzyme
PMID
Ortholog
Displaying entries 11 - 20 of 91 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
100071381 HORSE09849
100077524 ORNAN26940
100172963 PONAB23289
100181980 CIOIN00171
100192316 SHEEP13594
100304971 ICTPU35343
100355022 RABIT08802
100390439 CALJA10850
100469654 AILME18284
100548080 MELGA06428
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024