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Standards Ontologies Notations
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

Summary
Gene Symbol
  • HADHA
Organism
Chlorocebus sabaeus (green monkey)
NCBI Gene
103220642
KEGG Gene ID
csab:103220642
PubChem
103220642
Annotation
Keyword
  • Acetylation
  • Fatty acid metabolism
  • Lyase
  • Multifunctional enzyme
  • NAD
  • Oxidoreductase
  • Reference proteome
Proteins
Displaying 1 entry
UniProt Protein Name
A0A0D9R8Q2
Annotation information from UniProt.
Gene Ontology (GO)
Displaying 1 entry
GO Term Evidence Code PMID
fatty acid beta-oxidation
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Cercopithecoidea
Group Name
trifunctional enzyme subunit alpha, mitochondrial
Functional Category
  • H: Coenzyme transport and metabolism
  • I: Lipid transport and metabolism
  • J: Translation, ribosomal structure and biogenesis
  • Q: Secondary metabolites biosynthesis, transport and catabolism
Displaying all 9 entries
Gene Ontology
3-hydroxyacyl-CoA dehydrogenase activity
NAD+ binding
cardiolipin acyl-chain remodeling
catalytic activity
fatty acid beta-oxidation
fatty acid metabolic process
lyase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity
Displaying all 9 entries
InterPro
3-hydroxyacyl-CoA dehydrogenase, C-terminal
3-hydroxyacyl-CoA dehydrogenase, NAD binding
3-hydroxyacyl-CoA dehydrogenase, conserved site
6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
ClpP/crotonase-like domain superfamily
Enoyl-CoA hydratase/isomerase, conserved site
Enoyl-CoA hydratase/isomerase
Fatty acid oxidation complex, alpha subunit, mitochondrial
NAD(P)-binding domain superfamily
KEGG BRITE Database
Orthology
K07515
Name
enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
References
Rhea

RHEA:76647

(3S)-3-hydroxyadipyl-CoA
H2O + (E)-2,3-didehydroadipoyl-CoA
Enzyme
PMID

RHEA:16105

a (3S)-3-hydroxyacyl-CoA
H2O + a (2E)-enoyl-CoA
Enzyme
PMID

RHEA:20724

a 4-saturated-(3S)-3-hydroxyacyl-CoA
H2O + a (3E)-enoyl-CoA
Enzyme
PMID
Ortholog
Displaying entries 51 - 60 of 91 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
103735655 NANGA18681
103824695 SERCA22334
104677892 61622_0:004577 RHIRO06113
105479788 9545_0:004ac1 MACNE22182
105517670 336983_0:0003c4
105534008 9568_0:000ae1 MANLE02513
105578503 9531_0:003c33 CERAT08217
105706957 AOTNA41382
105816928 PROCO06580
107550361 SINGR71047
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024