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mannoside acetylglucosaminyltransferase 4, isoenzyme B

Summary

Gene Symbol

Mgat4b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

103534

KEGG Gene ID

mmu:103534

PubChem

103534

Alliance of Genome Resources

MGI:2143974

Annotation

Keyword

Coiled coil
Glycoprotein
Glycosyltransferase
Golgi apparatus
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q812F8	N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein glycosylation	ISS
protein glycosylation	ISO
protein N-linked glycosylation	IGI	20015870
protein N-linked glycosylation	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
Golgi membrane	IEA
endoplasmic reticulum	IBA
endoplasmic reticulum-Golgi intermediate compartment	IBA
Golgi stack	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

Golgi stack

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
acetylglucosaminyltransferase activity	IDA	20015870
acetylglucosaminyltransferase activity	IBA
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	ISS
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	ISO
glycosyltransferase activity	IDA	24619415

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
acetylglucosaminyltransferase activity
protein N-linked glycosylation

Displaying 1 entry
InterPro
Glycosyl transferase family 54

KEGG BRITE Database

Orthology

K00738

Name

alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145]

References

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05987	2.4.1.145	G39213VZ	G29011JC

Rhea

RHEA:16057

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.145

PMID

Ortholog

Displaying entries **1 - 10** of 70 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	11282	ZFIN:ZDB-GENE-040704-19	HUMAN82718
Drosophila melanogaster	11320	FB:FBgn0036446
Danio rerio	39608	ZFIN:ZDB-GENE-040704-19
Drosophila melanogaster	67555	FB:FBgn0036446
Danio rerio	103534	ZFIN:ZDB-GENE-040704-19
Drosophila melanogaster	152586	FB:FBgn0036446
Drosophila melanogaster	269181	FB:FBgn0036446
Rattus norvegicus	303100	ZFIN:ZDB-GENE-040704-19	RATNO02165
Drosophila melanogaster	304646	FB:FBgn0036446
Drosophila melanogaster	367252	FB:FBgn0036446

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Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements