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Guidelines

MIRAGE

3-hydroxy-3-methylglutaryl-CoA synthase 1

Summary

Gene Symbol

HMGCS1

Organism

Rhinopithecus roxellana (golden snub-nosed monkey)

External Links

NCBI Gene: 104662175
KEGG Gene ID: rro:104662175
PubChem: 104662175

Annotation

Keyword

Cholesterol biosynthesis
Cytoplasm
Reference proteome
Transferase

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K6RIH9	3-hydroxy-3-methylglutaryl coenzyme A synthase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
acetyl-CoA metabolic process	IEA	22301074 30032202
farnesyl diphosphate biosynthetic process, mevalonate pathway	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

amide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying 1 entry
GO Term	Evidence Code	PMID
hydroxymethylglutaryl-CoA synthase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, acyl groups converted into alkyl on transfer [inference]

hydroxymethylglutaryl-CoA synthase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

hydroxymethylglutaryl-CoA synthase A

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
acetyl-CoA metabolic process
ergosterol biosynthetic process
farnesyl diphosphate biosynthetic process, mevalonate pathway
hydroxymethylglutaryl-CoA synthase activity
transferase activity

Displaying **all 5** entries
InterPro
Hydroxymethylglutaryl-CoA synthase, eukaryotic
Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain
Hydroxymethylglutaryl-coenzyme A synthase, N-terminal
Hydroxymethylglutaryl-coenzyme A synthase, active site
Thiolase-like

KEGG BRITE Database

Orthology

K01641

Name

hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]

References

8566777

Rhea

H₂O + acetoacetyl-CoA + acetyl-CoA

H⁺ + (3S)-hydroxy-3-methylglutaryl-CoA + CoA

Enzyme

2.3.3.10

PMID

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3157		HUMAN79047
Rattus norvegicus	29637		RATNO23637
Mus musculus	208715		MOUSE11815
Danio rerio	394060		DANRE00551
Bos taurus	407767		BOVIN15976
Pan troglodytes	461892		PANTR35622
Canis lupus familiaris	479344		CANLF14974
Monodelphis domestica	100012956		MONDO18013
Equus caballus	100065037		HORSE20184
Ornithorhynchus anatinus	100075498		ORNAN17441

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Last updated: April 7, 2025