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angiotensin I converting enzyme

Summary

Gene Symbol

LOC105483045

Organism

Macaca nemestrina (pig-tailed macaque)

External Links

NCBI Gene: 105483045
PubChem: 105483045

Annotation

Keyword

Carboxypeptidase
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Signal
Transmembrane helix
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K6BQJ6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
regulation of systemic arterial blood pressure by renin-angiotensin	IEA	30032202
positive regulation of systemic arterial blood pressure	IEA	30032202
proteolysis	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

multicellular organismal process [inference]

system process [inference]

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin

biological regulation [inference]

regulation of biological quality [inference]

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin

positive regulation of blood pressure [inference]

positive regulation of systemic arterial blood pressure

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
carboxypeptidase activity
metallopeptidase activity	IEA	22301074 30032202
peptidyl-dipeptidase activity	IEA	22301074 30032202
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

angiotensin-converting enzyme

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
carboxypeptidase activity
hydrolase activity
metal ion binding
metallopeptidase activity
peptidyl-dipeptidase activity
positive regulation of systemic arterial blood pressure
proteolysis
regulation of systemic arterial blood pressure by renin-angiotensin

Displaying 1 entry
InterPro
Peptidase M2, peptidyl-dipeptidase A

Ortholog

Displaying entries **1 - 10** of 20 in total

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Pan paniscus	100980711	PANPA17686
Saimiri boliviensis boliviensis	101052117	SAIBB36499
Heterocephalus glaber	101701835	HETGA12181
Chinchilla lanigera	102027972	CHILA17794
Macaca fascicularis	102128376	MACFA14505
Cricetulus griseus	103158533	CRIGR10719
Nannospalax galili	103744762	NANGA20058