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Standards Ontologies Notations
phospholipase C beta 2

Summary
Gene Symbol
  • PLCB2
Organism
Macaca nemestrina (pig-tailed macaque)
NCBI Gene
105492354
KEGG Gene ID
mni:105492354
PubChem
105492354
Annotation
Keyword
  • Calcium
  • Coiled coil
  • Hydrolase
  • Lipid degradation
  • Metal-binding
  • Phosphoprotein
  • Reference proteome
  • Transducer
Proteins
Displaying 1 entry
UniProt Protein Name
A0A2K6B8P3
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Cercopithecoidea
Group Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
Functional Category
  • F: Nucleotide transport and metabolism
  • T: Signal transduction mechanisms
  • V: Defense mechanisms
Displaying all 7 entries
Gene Ontology
calcium ion binding
hydrolase activity
lipid metabolic process
metal ion binding
phosphatidylinositol phospholipase C activity
phosphatidylinositol-mediated signaling
release of sequestered calcium ion into cytosol
Displaying entries 1 - 10 of 14 in total
InterPro
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2, EF-hand domain
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2, catalytic domain
C2 domain superfamily
C2 domain
EF-hand domain pair
PLC-beta, PH domain
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta
Phosphatidylinositol-specific phospholipase C, X domain
Phosphoinositide phospholipase C family
KEGG BRITE Database
Orthology
K05858
Name
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
References
Rhea

RHEA:33179

H2O + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)
H+ + a 1,2-diacyl-sn-glycerol + 1D-myo-inositol 1,4,5-trisphosphate
Enzyme
PMID
Ortholog
Displaying entries 11 - 20 of 80 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
100386921 CALJA00836
100458716 PONAB09314
100474779 AILME18891
100551754 ANOCA16150
100606558 NOMLE31610
100706825 ORENI32073
100714143 CAVPO06604
100760731 CRIGR23262
100856190 CANLF12386
100929015 SARHA10996
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024