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ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

Summary

Gene Symbol

ST8SIA1

Organism

Microcebus murinus (gray mouse lemur)

External Links

NCBI Gene: 105882799
KEGG Gene ID: mmur:105882799
PubChem: 105882799

Annotation

Keyword

Disulfide bond
Glycoprotein
Golgi apparatus
Reference proteome
Signal-anchor
Sphingolipid metabolism
Transferase
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A8C5UR75	Alpha-2,8-sialyltransferase 8A Ganglioside GD3 synthase Sialyltransferase 8A Sialyltransferase St8Sia I
A0A8B7HSI0	Alpha-2,8-sialyltransferase 8A Ganglioside GD3 synthase Sialyltransferase 8A Sialyltransferase St8Sia I
A0A8B7HUJ3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein glycosylation	IEA	22301074 30032202
oligosaccharide metabolic process	IEA	30032202
N-glycan processing	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

Displaying 1 entry
GO Term	Evidence Code	PMID
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity [inference]

alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Sialyltransferase

Functional Category

H: Coenzyme transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
sialyltransferase activity
transferase activity

Displaying **all 2** entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29

KEGG BRITE Database

Orthology

K03371

Name

alpha-N-acetylneuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.3.8]

References

8058740

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R13175	2.4.3.8	G32254QI	G50116PC
R06032	2.4.3.8	G01767JJ	G70647TI
R05947	2.4.3.8	G98544DH	G93899SO
R05940	2.4.3.8	G91237TK	G98544DH

Rhea

RHEA:19313

an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + H⁺ + CMP

Enzyme

2.4.3.8

PMID

Ortholog

Displaying entries **21 - 30** of 80 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Cricetulus griseus	100768920		CRIGR10976
Sarcophilus harrisii	100920916		SARHA14789
Otolemur garnettii	100950426	30611_0:002616	OTOGA09784
Pan paniscus	100970748		PANPA09804
Papio anubis	101010038		PAPAN39891
Saimiri boliviensis boliviensis	101042881		SAIBB11139
Felis catus	101093029		FELCA15565
Ovis aries	101117321		SHEEP14807
Gorilla gorilla gorilla	101134419		GORGO06517
Tursiops truncatus	101321581		TURTR04764

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements