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retinal pigment epithelium-derived rhodopsin homolog

Summary

Gene Symbol

RRH

Organism

Homo sapiens (human)

External Links

NCBI Gene

10692

PubChem

10692

Alliance of Genome Resources

HGNC:10450

Annotation

Keyword

Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Retinal protein
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O14718

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	IBA
visual perception	IEA
phototransduction	IBA
detection of visible light	IEA
cellular response to light stimulus	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

detection of light stimulus [inference]

cellular response to light stimulus

cellular response to radiation [inference]

cellular response to light stimulus

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
photoreceptor outer segment
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

photoreceptor outer segment

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	TAS	9275222
protein binding	IPI	32296183
G protein-coupled photoreceptor activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled photoreceptor activity

photoreceptor activity [inference]

G protein-coupled photoreceptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Opsin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
cellular response to light stimulus
phototransduction
visual perception

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Visual pigments (opsins) retinal binding site

Ortholog

Displaying entries **1 - 10** of 64 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	10692	Xenbase:XB-GENE-6076482
Mus musculus	20132	Xenbase:XB-GENE-6076482	MOUSE37501
Rattus norvegicus	310869		RATNO25272
Bos taurus	539343		BOVIN31067
Canis lupus familiaris	610525		CANLF13152
Macaca mulatta	698241		MACMU37303
Pan troglodytes	736907		PANTR34324
Equus caballus	100064319		HORSE27183
Callithrix jacchus	100389248		CALJA28477
Pongo abelii	100454286		PONAB27821