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peptidylglycine alpha-amidating monooxygenase

Summary

Gene Symbol

pam

Organism

Pygocentrus nattereri (red-bellied piranha)

External Links

NCBI Gene: 108427288
PubChem: 108427288

Annotation

Keyword

Calcium
Copper
Disulfide bond
Glycoprotein
Lyase
Metal-binding
Monooxygenase
Multifunctional enzyme
Repeat
Signal
Transmembrane helix
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A3B4CRU0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
peptide metabolic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process

organic substance metabolic process [inference]

organonitrogen compound metabolic process [inference]

peptide metabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074
extracellular region	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IEA	22301074
peptidylamidoglycolate lyase activity
copper ion binding	IEA	22301074
peptidylglycine monooxygenase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [inference]

peptidylglycine monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [inference]

peptidylglycine monooxygenase activity

lyase activity [inference]

carbon-nitrogen lyase activity [inference]

amidine-lyase activity [inference]

peptidylamidoglycolate lyase activity

catalytic activity, acting on a protein [inference]

peptidylamidoglycolate lyase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

peptidyl-glycine alpha-amidating monooxygenase

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
catalytic activity
lyase activity
metal ion binding
peptide metabolic process
peptidylglycine monooxygenase activity

Displaying **all 3** entries
InterPro
NHL repeat
Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase
Six-bladed beta-propeller, TolB-like

Ortholog

Displaying entries **31 - 40** of **232** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mustela putorius furo	101671790			MUSPF06198
Heterocephalus glaber	101716909			HETGA01432
Ficedula albicollis	101821831			FICAL10147
Macaca fascicularis	101926659			MACFA35994
Chrysemys picta bellii	101942761			CHRPI15051
Chinchilla lanigera	102030078			CHILA05751
Capra hircus	102190130			CAPHI26921
Xiphophorus maculatus	102227462	8083_0:001dde
Haplochromis burtoni	102313014			HAPBU25381
Latimeria chalumnae	102348819			LATCH15325

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024