checkpoint kinase 1

Summary
Gene Symbol
  • CHEK1
Organism
Homo sapiens (human)
NCBI Gene
1111
PubChem
1111
Alliance of Genome Resources
JoGo
CHEK1
TogoVar
CHEK1
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Alternative splicing
  • Cell cycle
  • Chromosome
  • Cytoskeleton
  • DNA repair
  • Disease variant
  • Isopeptide bond
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Serine/threonine-protein kinase
  • Ubl conjugation
Proteins
Displaying all 3 entries
UniProt Protein Name
O14757
  • CHK1 checkpoint homolog
  • Cell cycle checkpoint kinase
  • Checkpoint kinase-1
B4DT73
E7EPP6
Gene Ontology (GO)
GO Hierarchy
Displaying entries 26 - 28 of 28 in total
GO Term Evidence Code PMID
histone H3S57 kinase activity
histone H3T45 kinase activity
histone H2AT120 kinase activity
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
protein kinase
Functional Category
  • E: Amino acid transport and metabolism
  • G: Carbohydrate transport and metabolism
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:1793 pancreatic cancer

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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