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cadherin-related 23

Summary

Gene Symbol

Cdh23

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

114102

PubChem

114102

Alliance of Genome Resources

RGD:619760

Annotation

Keyword

Calcium
Cell adhesion
Cell membrane
Glycoprotein
Hearing
Metal-binding
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P58365	Otocadherin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
calcium ion transport	ISO
calcium ion transport	IEA
homophilic cell adhesion via plasma membrane adhesion molecules	IEA
sensory perception of sound	ISO
sensory perception of sound	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

mechanoreceptor differentiation [inference]

inner ear receptor cell differentiation [inference]

inner ear auditory receptor cell differentiation

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

inner ear receptor cell stereocilium organization

auditory receptor cell stereocilium organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus

sensory perception of mechanical stimulus [inference]

sensory perception of sound

equilibrioception

behavior [inference]

locomotory behavior

adult locomotory behavior

adult behavior [inference]

adult locomotory behavior

photoreceptor cell maintenance

developmental process [inference]

anatomical structure morphogenesis [inference]

embryonic morphogenesis [inference]

inner ear morphogenesis

anatomical structure development [inference]

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

mechanoreceptor differentiation [inference]

inner ear receptor cell differentiation [inference]

inner ear auditory receptor cell differentiation

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

response to stimulus [inference]

response to external stimulus [inference]

reflex [inference]

righting reflex

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport

organic substance transport [inference]

calcium ion transport

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
photoreceptor inner segment	ISO
photoreceptor inner segment	IEA
centrosome	ISO
centrosome	IEA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

photoreceptor inner segment

microtubule organizing center [inference]

centrosome

membrane [inference]

plasma membrane

cell junction [inference]

synapse

ribbon synapse [inference]

anchoring junction [inference]

cell-cell junction

stereocilium tip

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

non-motile cilium [inference]

9+2 non-motile cilium [inference]

kinocilium

neuron projection [inference]

actin-based cell projection [inference]

stereocilium

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

non-motile cilium [inference]

9+2 non-motile cilium [inference]

kinocilium

apical part of cell

Displaying **all 3** entries
GO Term	Evidence Code	PMID
calcium ion binding	IBA
calcium ion binding	IEA
protein binding	IPI	23329832

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cadherin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 3** entries
InterPro
Cadherin conserved site
Cadherin-like superfamily
Cadherin-like

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
apical part of cell	PMID:15882573

Ortholog

Displaying entries **1 - 10** of 51 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	22295	Xenbase:XB-GENE-957613	MOUSE01878
Danio rerio	41441	ZFIN:ZDB-GENE-040513-7
Homo sapiens	64072	Xenbase:XB-GENE-957613	HUMAN01547
Drosophila melanogaster	92211	FB:FBgn0037963
Xenopus tropicalis	114102	Xenbase:XB-GENE-957613
Pan troglodytes	450516		PANTR00842
Macaca mulatta	709433		MACMU45865
Bos taurus	784716		BOVIN22492
Ornithorhynchus anatinus	100077192		ORNAN18135
Equus caballus	100146534		HORSE18010

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements