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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cholinergic receptor nicotinic beta 4 subunit
Summary
- Gene Symbol
-
- CHRNB4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P30926 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor signaling pathway | ||
| positive regulation of transmission of nerve impulse | ||
| synaptic transmission, cholinergic | ||
| excitatory postsynaptic potential | ||
| ion transmembrane transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| postsynaptic membrane |
|
|
| postsynaptic specialization membrane | ||
| plasma membrane | ||
| tertiary granule membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| ligand-gated monoatomic ion channel activity | ||
| acetylcholine receptor activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- AcetylCholine Receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:1324 | lung cancer | |
| DOID:1596 | depressive disorder | |
| DOID:3748 | esophagus squamous cell carcinoma | |
| DOID:3907 | lung squamous cell carcinoma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:5409 | lung small cell carcinoma | |
| DOID:809 | cocaine abuse | |
| DOID:8618 | oral cavity cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100920846 | SARHA14642 | |||
| 100940471 | OTOGA16534 | |||
| 100991460 | 9597_0:003dc1 | PANPA13920 | ||
| 101002364 | PAPAN37160 | |||
| 101033144 | SAIBB37390 | |||
| 101089940 | FELCA12839 | |||
| 101123499 | SHEEP07827 | |||
| 101140618 | 9595_0:004269 | GORGO09729 | ||
| 101159423 | ORYLA12623 | |||
| 101327454 | TURTR03411 |
