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fructose-bisphosphatase 2

Summary

Gene Symbol

Fbp2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

114508

PubChem

114508

Alliance of Genome Resources

RGD:620930

Annotation

Keyword

Allosteric enzyme
Calcium
Carbohydrate metabolism
Cell junction
Cytoplasm
Gluconeogenesis
Hydrolase
Magnesium
Metal-binding
Nucleus
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9Z1N1	D-fructose-1,6-bisphosphate 1-phosphohydrolase 2 Muscle FBPase
A6KQB2	D-fructose-1,6-bisphosphate 1-phosphohydrolase 2 Muscle FBPase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
fructose metabolic process	IBA
sucrose biosynthetic process	IBA
fructose 6-phosphate metabolic process	IBA
fructose 1,6-bisphosphate metabolic process	IBA
gluconeogenesis	IBA IDA IEA	11440903 4353083

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

organophosphate metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

sucrose metabolic process [inference]

sucrose biosynthetic process

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

sucrose metabolic process [inference]

sucrose biosynthetic process

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organophosphate metabolic process [inference]

carbohydrate derivative metabolic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

organophosphate metabolic process [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleus	IEA
anchoring junction	IEA
Z disc	IEA
cytosol	IBA ISO
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Z disc

cell junction [inference]

anchoring junction

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
fructose 1,6-bisphosphate 1-phosphatase activity	IBA IDA	11440903 4353083 8570009
identical protein binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

carbohydrate phosphatase activity [inference]

sugar-phosphatase activity [inference]

fructose 1,6-bisphosphate 1-phosphatase activity

binding [inference]

protein binding [inference]

identical protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:11064

H₂O + β-D-fructose 1,6-bisphosphate

phosphate + β-D-fructose 6-phosphate

Enzyme

3.1.3.11

PMID

Ortholog

Displaying entries **21 - 30** of 64 in total

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Species	Gene ID	Orthologous MAtrix
Ailuropoda melanoleuca	100475474	AILME11675
Mustela putorius furo	101677003	MUSPF02723
Felis catus	101084578	FELCA29860
Panthera leo	122204921	PANLE25474
Balaenoptera musculus	118897362	BALMU13117
Loxodonta africana	100676689	LOXAF16894
Equus caballus	100061491	HORSE21988
Equus caballus	100063910	HORSE21988
Bos taurus	514066	BOVIN34903
Capra hircus	102185744	CAPHI29460