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fructose-bisphosphatase 2

Summary

Gene Symbol

FBP2

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 514066
KEGG Gene ID: bta:514066
PubChem: 514066

Annotation

Keyword

Calcium
Carbohydrate metabolism
Cell junction
Cytoplasm
Gluconeogenesis
Hydrolase
Magnesium
Metal-binding
Nucleus
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q2KJJ9	D-fructose-1,6-bisphosphate 1-phosphohydrolase 2 Muscle FBPase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
sucrose biosynthetic process	IEA	30032202
fructose metabolic process	IEA	30032202
fructose 6-phosphate metabolic process	IEA	30032202
gluconeogenesis	IEA	30032202
fructose 1,6-bisphosphate metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

organophosphate metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

sucrose metabolic process [inference]

sucrose biosynthetic process

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

sucrose metabolic process [inference]

sucrose biosynthetic process

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organophosphate metabolic process [inference]

carbohydrate derivative metabolic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

organophosphate metabolic process [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleus
cytoplasm	IEA	30032202
cytosol	IEA	30032202
Z disc
anchoring junction

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell junction [inference]

anchoring junction

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
fructose 1,6-bisphosphate 1-phosphatase activity	IEA	22301074 30032202
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

carbohydrate phosphatase activity [inference]

sugar-phosphatase activity [inference]

fructose 1,6-bisphosphate 1-phosphatase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

fructose-1,6-bisphosphatase I

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
fructose 1,6-bisphosphate 1-phosphatase activity
fructose 1,6-bisphosphate metabolic process
fructose 6-phosphate metabolic process
fructose metabolic process
gluconeogenesis
hydrolase activity
metal ion binding
phosphoric ester hydrolase activity
sucrose biosynthetic process

Displaying **all 5** entries
InterPro
Fructose-1,6-bisphosphatase class 1
Fructose-1,6-bisphosphatase, active site
Fructose-1,6-bisphosphatase
Fructose-1-6-bisphosphatase class 1, C-terminal
Fructose-1-6-bisphosphatase class I, N-terminal

KEGG BRITE Database

Orthology

K03841

Name

fructose-1,6-bisphosphatase I [EC:3.1.3.11]

References

7589895

Rhea

RHEA:11064

H₂O + β-D-fructose 1,6-bisphosphate

phosphate + β-D-fructose 6-phosphate

Enzyme

3.1.3.11

PMID

Ortholog

Displaying entries **1 - 10** of 59 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	8789	HUMAN97654
Mus musculus	14120	MOUSE12210
Rattus norvegicus	114508	RATNO12451
Pan troglodytes	465261	PANTR44369
Canis lupus familiaris	476300	CANLF00378
Monodelphis domestica	100013237	MONDO28641
Equus caballus	100061491	HORSE21988
Equus caballus	100063910	HORSE21988
Taeniopygia guttata	100219012	TAEGU31882
Callithrix jacchus	100408581	CALJA18245

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Acknowledgements