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MIRAGE
fructose-bisphosphatase 2
Summary
- Gene Symbol
-
- FBP2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Allosteric enzyme
- Calcium
- Carbohydrate metabolism
- Cell junction
- Cytoplasm
- Disease variant
- Gluconeogenesis
- Hydrolase
- Leukodystrophy
- Magnesium
- Metal-binding
- Nucleus
- Phosphoprotein
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| O00757 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| sucrose biosynthetic process |
|
|
| fructose metabolic process | ||
| fructose 6-phosphate metabolic process | ||
| gluconeogenesis | ||
| gluconeogenesis |
GO Hierarchy
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| fructose 1,6-bisphosphate 1-phosphatase activity | ||
| identical protein binding | ||
| metal ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- fructose-1,6-bisphosphatase I
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
KEGG BRITE Database
Rhea
Disease
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0000737 | Irritability |
| HP:0001288 | Gait disturbance |
| HP:0002415 | Leukodystrophy |
| HP:0002500 | Abnormal cerebral white matter morphology |
| HP:0003593 | Infantile onset |
| HP:0007359 | Focal-onset seizure |
| HP:0011968 | Feeding difficulties |
| Disease ID | Disease Name |
|---|---|
| OMIM:619864 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2203 | SGD:S000004369 | ||
| 8789 | Xenbase:XB-GENE-943524 | ||
| 14120 | Xenbase:XB-GENE-943524 | MOUSE12210 | |
| 14121 | SGD:S000004369 | ||
| 24362 | SGD:S000004369 | ||
| 114508 | Xenbase:XB-GENE-943524 | RATNO12451 | |
| 465261 | PANTR44369 | ||
| 476300 | CANLF00378 | ||
| 514066 | BOVIN34903 | ||
| 851092 | Xenbase:XB-GENE-943524 |
