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actinin alpha 2

Summary

Gene Symbol

Actn2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11472

PubChem

11472

Alliance of Genome Resources

MGI:109192

Annotation

Keyword

Actin-binding
Calcium
Coiled coil
Cytoplasm
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9JI91	Alpha-actinin skeletal muscle isoform 2 F-actin cross-linking protein
Q5FW75

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **26 - 30** of 33 in total

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GO Term	Evidence Code	PMID
negative regulation of potassium ion transmembrane transporter activity	ISO
positive regulation of potassium ion transmembrane transporter activity	ISO
negative regulation of protein localization to cell surface	ISO
negative regulation of protein localization to cell surface	IEA
positive regulation of endocytic recycling	ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating angiotensin-activated signaling pathway

angiotensin-activated signaling pathway [inference]

phospholipase C-activating angiotensin-activated signaling pathway

actin filament-based process [inference]

actin cytoskeleton organization

actomyosin structure organization [inference]

sarcomere organization

postsynaptic actin cytoskeleton organization

cellular developmental process [inference]

cell development [inference]

muscle cell development

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

actomyosin structure organization [inference]

sarcomere organization

postsynaptic actin cytoskeleton organization

postsynaptic cytoskeleton organization [inference]

postsynaptic actin cytoskeleton organization

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

microspike assembly

cell junction assembly [inference]

cell-substrate junction assembly [inference]

focal adhesion assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

microspike assembly

plasma membrane bounded cell projection organization [inference]

plasma membrane bounded cell projection assembly [inference]

microspike assembly

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

cell junction organization [inference]

cell junction assembly [inference]

cell-substrate junction assembly [inference]

focal adhesion assembly

cell-substrate junction organization [inference]

cell-substrate junction assembly [inference]

focal adhesion assembly

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

muscle cell development

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

cellular developmental process [inference]

cell development [inference]

muscle cell development

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of endocytic recycling

regulation of endocytic recycling [inference]

positive regulation of endocytic recycling

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of ion transmembrane transporter activity [inference]

regulation of potassium ion transmembrane transporter activity [inference]

regulation of cation channel activity [inference]

positive regulation of cation channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

regulation of cation channel activity [inference]

positive regulation of cation channel activity

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of potassium ion transport [inference]

negative regulation of potassium ion transport

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of potassium ion transport

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

regulation of cation channel activity [inference]

positive regulation of cation channel activity

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

positive regulation of potassium ion transport

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of potassium ion transport

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of endocytic recycling

positive regulation of transporter activity [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

positive regulation of potassium ion transport

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of potassium ion transport

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

regulation of vesicle-mediated transport [inference]

regulation of endocytic recycling [inference]

positive regulation of endocytic recycling

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of endocytic recycling

regulation of endocytic recycling [inference]

positive regulation of endocytic recycling

regulation of protein localization [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell surface

regulation of protein localization to cell surface [inference]

negative regulation of protein localization to cell surface

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of intracellular transport [inference]

positive regulation of endocytic recycling

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

positive regulation of protein-containing complex disassembly [inference]

positive regulation of protein depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of endocytic recycling

positive regulation of transporter activity [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

positive regulation of potassium ion transport

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of protein localization [inference]

negative regulation of protein localization to cell surface

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of potassium ion transport

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating angiotensin-activated signaling pathway

angiotensin-activated signaling pathway [inference]

phospholipase C-activating angiotensin-activated signaling pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of ion transmembrane transporter activity [inference]

regulation of potassium ion transmembrane transporter activity [inference]

regulation of cation channel activity [inference]

positive regulation of cation channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

regulation of cation channel activity [inference]

positive regulation of cation channel activity

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of intracellular transport [inference]

positive regulation of endocytic recycling

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of ion transmembrane transporter activity [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transporter activity

positive regulation of cation channel activity

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

positive regulation of protein-containing complex disassembly [inference]

positive regulation of protein depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity

negative regulation of protein localization [inference]

negative regulation of protein localization to cell surface

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

regulation of protein-containing complex disassembly [inference]

positive regulation of protein-containing complex disassembly [inference]

positive regulation of protein depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

regulation of protein depolymerization [inference]

regulation of actin filament depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

positive regulation of protein depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

positive regulation of protein-containing complex disassembly [inference]

positive regulation of protein depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

regulation of supramolecular fiber organization [inference]

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of endocytic recycling

regulation of endocytic recycling [inference]

positive regulation of endocytic recycling

regulation of protein localization [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell surface

regulation of protein localization to cell surface [inference]

negative regulation of protein localization to cell surface

regulation of vesicle-mediated transport [inference]

regulation of endocytic recycling [inference]

positive regulation of endocytic recycling

regulation of biological quality [inference]

regulation of membrane potential

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament depolymerization [inference]

positive regulation of actin filament depolymerization [inference]

actin filament uncapping

regulation of molecular function [inference]

regulation of transporter activity [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of ion transmembrane transporter activity [inference]

regulation of potassium ion transmembrane transporter activity [inference]

regulation of cation channel activity [inference]

positive regulation of cation channel activity

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of transporter activity [inference]

positive regulation of ion transmembrane transporter activity [inference]

negative regulation of molecular function [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity

positive regulation of molecular function [inference]

positive regulation of transporter activity [inference]

positive regulation of ion transmembrane transporter activity [inference]

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
striated muscle thin filament	TAS	8618961
plasma membrane	ISO
plasma membrane	IBA
focal adhesion	ISO
focal adhesion	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction

synapse [inference]

glutamatergic synapse

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

myofilament [inference]

striated muscle thin filament

cell projection

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

filopodium

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton [inference]

postsynaptic actin cytoskeleton

cortical cytoskeleton [inference]

cortical actin cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic actin cytoskeleton

postsynaptic specialization, intracellular component [inference]

postsynaptic density, intracellular component

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton [inference]

postsynaptic actin cytoskeleton

cortical cytoskeleton [inference]

cortical actin cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic actin cytoskeleton

postsynaptic specialization, intracellular component [inference]

postsynaptic density, intracellular component

Displaying entries **6 - 10** of 25 in total

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GO Term	Evidence Code	PMID
cytoskeletal protein binding	ISO
cytoskeletal protein binding	IDA	10391924
protein domain specific binding	ISO
LIM domain binding	IPI	10391924
nuclear receptor coactivator activity

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of cytoskeleton [inference]

structural constituent of postsynaptic actin cytoskeleton

structural constituent of synapse [inference]

structural constituent of postsynapse [inference]

structural constituent of postsynaptic actin cytoskeleton

binding [inference]

protein binding

cytoskeletal protein binding

actin binding [inference]

actin filament binding

protein domain specific binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

ion binding [inference]

anion binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

cation binding [inference]

metal ion binding [inference]

calcium ion binding

protein-containing complex binding [inference]

actin filament binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

transcription regulator activity [inference]

transcription coregulator activity [inference]

transcription coactivator activity

nuclear receptor coactivator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Alpha actinin

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
actin binding
actin cytoskeleton organization
actin filament binding
calcium ion binding

Displaying **all 8** entries
InterPro
Actinin-type actin-binding domain, conserved site
CH domain superfamily
Calponin homology domain
EF-hand domain pair
EF-hand domain
EF-hand, Ca insensitive
Spectrin repeat
Spectrin/alpha-actinin

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements