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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ADAM metallopeptidase domain 12
Summary
- Gene Symbol
-
- Adam12
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cell adhesion
- Cleavage on pair of basic residues
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Metal-binding
- Metalloprotease
- Phosphoprotein
- Reference proteome
- SH3-binding
- Signal
- Transmembrane helix
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q61824 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| positive regulation of angiogenesis | ||
| cell adhesion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| nucleoplasm |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| SH3 domain binding | ||
| metal ion binding | ||
| metalloendopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- disintegrin and metalloproteinase domain-containing protein 12
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:8398 | osteoarthritis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100157228 | PIGXX08692 | |||
| 100225378 | TAEGU26685 | |||
| 100341644 | RABIT14902 | |||
| 100408456 | CALJA07894 | |||
| 100459187 | PONAB02020 | |||
| 100599775 | NOMLE27063 | |||
| 100686018 | CANLF11576 | |||
| 100703495 | ORENI13677 | |||
| 100735152 | 10141_0:004a8a | CAVPO00781 | ||
| 100759770 | 10029_0:0025db |
