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angiotensin II receptor, type 1b

Summary

Gene Symbol

Agtr1b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11608

PubChem

11608

Alliance of Genome Resources

MGI:87965

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q8BU69
P29755	AT3 Angiotensin II type-1 receptor B
Q32MF7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 47 in total

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GO Term	Evidence Code	PMID
blood vessel development	IGI	9466969
response to hypoxia	IEA
kidney development	ISO
kidney development	IGI	9466969
regulation of systemic arterial blood pressure by circulatory renin-angiotensin	IGI	9466969

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

phospholipase C-activating angiotensin-activated signaling pathway

angiotensin-activated signaling pathway

phospholipase C-activating angiotensin-activated signaling pathway

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction [inference]

Rho protein signal transduction

second-messenger-mediated signaling [inference]

calcium-mediated signaling

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

cell motility [inference]

cell migration [inference]

cell chemotaxis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

renal system process [inference]

renal system process involved in regulation of systemic arterial blood pressure [inference]

renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure [inference]

maintenance of blood vessel diameter homeostasis by renin-angiotensin

nervous system process [inference]

nervous system process involved in regulation of systemic arterial blood pressure [inference]

brain renin-angiotensin system

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin [inference]

regulation of systemic arterial blood pressure by circulatory renin-angiotensin

regulation of blood volume by renin-angiotensin [inference]

brain renin-angiotensin system

maintenance of blood vessel diameter homeostasis by renin-angiotensin

behavior [inference]

feeding behavior [inference]

drinking behavior

developmental process [inference]

anatomical structure development [inference]

blood vessel development

animal organ development [inference]

kidney development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

response to stimulus [inference]

response to stress [inference]

response to hypoxia

defense response [inference]

inflammatory response

response to osmotic stress [inference]

response to salt stress

response to immobilization stress

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient

response to abiotic stimulus [inference]

response to osmotic stress [inference]

response to salt stress

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to estrogen

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to estrogen

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to ketone [inference]

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

response to nicotine

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

response to oxygen-containing compound [inference]

response to ketone [inference]

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process

regulation of protein metabolic process [inference]

positive regulation of protein metabolic process

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process

regulation of protein metabolic process [inference]

positive regulation of protein metabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

positive regulation of protein metabolic process

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation [inference]

positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis

positive regulation of cell differentiation [inference]

positive regulation of macrophage derived foam cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of macrophage derived foam cell differentiation

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of branching involved in ureteric bud morphogenesis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of morphogenesis of a branching structure [inference]

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of morphogenesis of an epithelium [inference]

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of animal organ morphogenesis [inference]

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of cell differentiation [inference]

regulation of macrophage derived foam cell differentiation [inference]

positive regulation of macrophage derived foam cell differentiation

positive regulation of cell differentiation [inference]

positive regulation of macrophage derived foam cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of macrophage derived foam cell differentiation

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of kidney development [inference]

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

phospholipase C-activating angiotensin-activated signaling pathway

angiotensin-activated signaling pathway

phospholipase C-activating angiotensin-activated signaling pathway

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction [inference]

Rho protein signal transduction

second-messenger-mediated signaling [inference]

calcium-mediated signaling

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation [inference]

positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis

regulation of epithelial cell proliferation [inference]

regulation of endothelial cell proliferation [inference]

positive regulation of endothelial cell proliferation [inference]

positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis

regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [inference]

positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation [inference]

positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cell differentiation [inference]

regulation of macrophage derived foam cell differentiation [inference]

positive regulation of macrophage derived foam cell differentiation

positive regulation of cell differentiation [inference]

positive regulation of macrophage derived foam cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation [inference]

positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis

positive regulation of cell differentiation [inference]

positive regulation of macrophage derived foam cell differentiation

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction

positive regulation of multicellular organismal process [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of morphogenesis of a branching structure [inference]

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

regulation of blood pressure

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin [inference]

regulation of systemic arterial blood pressure by circulatory renin-angiotensin

regulation of blood volume by renin-angiotensin [inference]

brain renin-angiotensin system

maintenance of blood vessel diameter homeostasis by renin-angiotensin

positive regulation of blood pressure

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of lipase activity [inference]

positive regulation of phospholipase activity [inference]

positive regulation of phospholipase A2 activity

positive regulation of transferase activity [inference]

positive regulation of CoA-transferase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of lipase activity [inference]

positive regulation of phospholipase activity [inference]

positive regulation of phospholipase A2 activity

positive regulation of transferase activity [inference]

positive regulation of CoA-transferase activity

regulation of hydrolase activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of lipase activity [inference]

positive regulation of phospholipase activity [inference]

positive regulation of phospholipase A2 activity

regulation of lipase activity [inference]

regulation of phospholipase activity [inference]

positive regulation of phospholipase activity [inference]

positive regulation of phospholipase A2 activity

regulation of phospholipase A2 activity [inference]

positive regulation of phospholipase A2 activity

positive regulation of lipase activity [inference]

positive regulation of phospholipase activity [inference]

positive regulation of phospholipase A2 activity

regulation of transferase activity [inference]

positive regulation of transferase activity [inference]

positive regulation of CoA-transferase activity

regulation of CoA-transferase activity [inference]

positive regulation of CoA-transferase activity

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

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GO Term	Evidence Code	PMID
angiotensin type I receptor activity	ISS
angiotensin type I receptor activity	ISO
angiotensin type I receptor activity	IBA
angiotensin type II receptor activity	ISO
angiotensin type II receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

bradykinin receptor binding

protein dimerization activity [inference]

protein heterodimerization activity

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

angiotensin receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

angiotensin receptor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

type-1 angiotensin II receptor

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying entries **1 - 10** of 13 in total

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Gene Ontology
C-C chemokine binding
C-C chemokine receptor activity
angiotensin type I receptor activity
angiotensin type II receptor activity
angiotensin-activated signaling pathway
brain development
calcium-mediated signaling
cell chemotaxis
immune response
neurogenesis

Displaying **all 4** entries
InterPro
Angiotensin II receptor family
Angiotensin II receptor type 1
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **1 - 10** of **129** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	185	Xenbase:XB-GENE-478953	HUMAN72791
Caenorhabditis elegans	186	WB:WBGene00012084
Caenorhabditis elegans	187	WB:WBGene00012084
Caenorhabditis elegans	623	WB:WBGene00012084
Caenorhabditis elegans	624	WB:WBGene00012084
Xenopus tropicalis	7201	Xenbase:XB-GENE-478953
Xenopus tropicalis	11607	Xenbase:XB-GENE-478953
Xenopus tropicalis	11608	Xenbase:XB-GENE-478953
Caenorhabditis elegans	11609	WB:WBGene00012084
Caenorhabditis elegans	12061	WB:WBGene00012084

GlyTouCan

GlyComb

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LM-GlycoRepo

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OrthoDB (Group)

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Acknowledgements