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squalene epoxidase

Summary

Gene Symbol

SQLE

Organism

Passer montanus (Eurasian tree sparrow)

External Links

NCBI Gene: 120505198
KEGG Gene ID: pmoa:120505198
PubChem: 120505198

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol metabolic process	IEA	30032202
sterol biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074
endoplasmic reticulum	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
squalene monooxygenase activity	IEA	22301074 30032202
flavin adenine dinucleotide binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

squalene monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

squalene monooxygenase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

squalene

Functional Category

C: Energy production and conversion
H: Coenzyme transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
cholesterol metabolic process
ergosterol biosynthetic process
flavin adenine dinucleotide binding
oxidoreductase activity
squalene monooxygenase activity
sterol biosynthetic process
sterol metabolic process

Displaying **all 3** entries
InterPro
FAD/NAD(P)-binding domain superfamily
Squalene epoxidase
Squalene monooxygenase

KEGG BRITE Database

Orthology

K00511

Name

squalene monooxygenase [EC:1.14.14.17]

References

17852349

Ortholog

Displaying entries **21 - 30** of 44 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Camarhynchus parvulus	115901032	87175_0:000606
Corvus moneduloides	116455350	1196302_0:00029e
Chiroxiphia lanceolata	116792672	296741_0:0002e2
Catharus ustulatus	117001806	91951_0:0005e3
Molothrus ater	118702008	84834_0:000212
Motacilla alba alba	119697921	1094192_0:000536
Hirundo rustica	120751751	43150_0:000226
Onychostruthus taczanowskii	121337483	356909_0:001b1f
Pyrgilauda ruficollis	121349874	221976_0:000b9c
Corvus kubaryi	121668373	68294_0:001f89

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024