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adenosine A2a receptor

Summary

Gene Symbol

ADORA2A

Organism

Homo sapiens (human)

External Links

NCBI Gene

135

PubChem

135

Alliance of Genome Resources

HGNC:263

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix
Ubl conjugation

Proteins

Displaying **all 4** entries
UniProt	Protein Name
X5DNB4
P29274
A8K1F6
B3KVQ4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 52 in total

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GO Term	Evidence Code	PMID
synaptic transmission, dopaminergic	IEA
G protein-coupled adenosine receptor signaling pathway	IBA
response to amphetamine	IEA
regulation of DNA-templated transcription	IEA
regulation of transcription, DNA-templated	IEA

GO Hierarchy

biological process

cellular process [inference]

cell activation [inference]

glial cell activation [inference]

astrocyte activation

cell communication [inference]

cell-cell signaling

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

purinergic nucleotide receptor signaling pathway [inference]

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

apoptotic signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

multicellular organismal process [inference]

cell activation [inference]

glial cell activation [inference]

astrocyte activation

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

regulation of vascular permeability [inference]

negative regulation of vascular permeability

blood vessel diameter maintenance [inference]

vasodilation

blood circulation

renal system process [inference]

regulation of urine volume [inference]

positive regulation of urine volume

nervous system process [inference]

sensory perception

behavior [inference]

locomotory behavior

feeding behavior [inference]

eating behavior

coagulation [inference]

blood coagulation

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

anatomical structure development [inference]

system development [inference]

central nervous system development

response to stimulus [inference]

response to stress [inference]

defense response [inference]

response to chemical [inference]

response to xenobiotic stimulus

response to organic substance [inference]

response to organonitrogen compound [inference]

response to purine-containing compound

response to caffeine

response to amine [inference]

response to amphetamine

response to alkaloid [inference]

response to caffeine

response to organic cyclic compound [inference]

response to purine-containing compound

response to caffeine

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to purine-containing compound

response to caffeine

response to amine [inference]

response to amphetamine

response to alkaloid [inference]

response to caffeine

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

import into cell [inference]

endocytosis [inference]

phagocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, cholinergic [inference]

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic transmission, GABAergic [inference]

positive regulation of synaptic transmission, GABAergic

regulation of neurotransmitter secretion [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic transmission, glutamatergic [inference]

positive regulation of synaptic transmission, glutamatergic

presynaptic modulation of chemical synaptic transmission

signaling [inference]

cell-cell signaling

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of organic acid transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of amino acid transport [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of secretion by cell [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

regulation of neurotransmitter secretion [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of amine transport [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of amine transport [inference]

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

positive regulation of amine transport [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of amino acid transport [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of circadian rhythm [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of circadian rhythm [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of circadian rhythm [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of amine transport [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

positive regulation of multicellular organismal process [inference]

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of cell population proliferation

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

regulation of inflammatory response [inference]

negative regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

purinergic nucleotide receptor signaling pathway [inference]

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

apoptotic signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, cholinergic [inference]

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic transmission, GABAergic [inference]

positive regulation of synaptic transmission, GABAergic

regulation of neurotransmitter secretion [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic transmission, glutamatergic [inference]

positive regulation of synaptic transmission, glutamatergic

presynaptic modulation of chemical synaptic transmission

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of cell population proliferation

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

regulation of neurotransmitter secretion [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of multicellular organismal process [inference]

regulation of behavior [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

positive regulation of multicellular organismal process [inference]

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of postsynaptic membrane potential [inference]

regulation of vascular permeability [inference]

negative regulation of vascular permeability

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

regulation of body fluid levels [inference]

hemostasis [inference]

blood coagulation

regulation of urine volume [inference]

positive regulation of urine volume

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

vasodilation

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
intermediate filament	IEA
plasma membrane	TAS
plasma membrane	IDA	16339847 25644539
plasma membrane	IMP	21393508
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

neuron projection membrane [inference]

axolemma

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

glutamatergic synapse

neuron to neuron synapse [inference]

asymmetric synapse

leading edge membrane [inference]

neuron projection membrane [inference]

axolemma

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

cell body [inference]

neuronal cell body

presynaptic active zone

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

intermediate filament

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GO Term	Evidence Code	PMID
G protein-coupled adenosine receptor activity	IDA	21393508 21593763
G protein-coupled adenosine receptor activity	IBA
protein binding	IPI	11571652 12189203 16027149 16339847 16481441 17356572 17689978 19694902 23296780 28102227 28298427 28734904 29568380 31286866 32296183
calmodulin binding	EXP	25692595
calmodulin binding	IDA	25692595

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

G protein-coupled glutamate receptor binding [inference]

type 5 metabotropic glutamate receptor binding

glutamate receptor binding [inference]

G protein-coupled glutamate receptor binding [inference]

type 5 metabotropic glutamate receptor binding

calmodulin binding

cytoskeletal protein binding [inference]

actinin binding [inference]

alpha-actinin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled adenosine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Adenosine receptor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2841	asthma	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 94 in total

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Species	Gene ID	Orthologous MAtrix
Canis lupus familiaris	403960	CANLF10554
Pan troglodytes	458714	PANTR26183
Sus scrofa	503661	PIGXX07298
Danio rerio	561701	DANRE43524
Bos taurus	617828	BOVIN09973
Macaca mulatta	707641	MACMU02824
Macaca mulatta	707865	MACMU02824
Monodelphis domestica	100029653	MONDO01029
Equus caballus	100034039	HORSE40631
Cavia porcellus	100135473	CAVPO03577

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements